Effect of Pretransplant Dialysis Modality on Outcomes After Simultaneous Pancreas-Kidney Transplantation

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http://hdl.handle.net/10138/306059

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Räihä , J , Helanterä , I , Ekstrand , A , Nordin , A , Sallinen , V & Lempinen , M 2019 , ' Effect of Pretransplant Dialysis Modality on Outcomes After Simultaneous Pancreas-Kidney Transplantation ' , Annals of transplantation , vol. 24 , pp. 426-431 . https://doi.org/10.12659/AOT.916649

Title: Effect of Pretransplant Dialysis Modality on Outcomes After Simultaneous Pancreas-Kidney Transplantation
Author: Räihä, Juulia; Helanterä, Ilkka; Ekstrand, Agneta; Nordin, Arno; Sallinen, Ville; Lempinen, Marko
Contributor: University of Helsinki, Department of Surgery
University of Helsinki, HUS Abdominal Center
University of Helsinki, HUS Abdominal Center
University of Helsinki, HUS Abdominal Center
University of Helsinki, Staff Services
University of Helsinki, HUS Abdominal Center
Date: 2019-07-19
Language: eng
Number of pages: 6
Belongs to series: Annals of transplantation
ISSN: 1425-9524
URI: http://hdl.handle.net/10138/306059
Abstract: Background: Pretransplant dialysis modality may affect outcome after simultaneous pancreas-kidney transplantation (SPKT), and it has been suspected that peritoneal dialysis (PD) is associated with more postoperative complications compared to hemodialysis (HD). The aim of this study was to evaluate whether pretransplant dialysis modality affects the risk for postoperative complications in SPKT recipients. Material/ Methods: This was a retrospective longitudinal cohort study of all patients undergoing SPKT from 2010 to 2017, during which 99 simultaneous pancreas-kidney transplantations were performed. Three pre-emptive transplantations were excluded. Patient groups receiving PD (n=59) or HD (n=37) were similar regarding baseline characteristics. All complications occurring during the first 3 months after transplantation, as well as patient and graft survival, were analyzed. Results: There were no significant differences in postoperative complications between groups, with similar rates of intraabdominal infections (8% in HD vs. 10% in PD), pancreatitis (16% in HD vs. 17% in PD), gastrointestinal bleedings (22% in HD vs. 10% in PD), and relaparotomies (27% in HD vs. 24% in PD). None of the patients had venous graft thrombosis. Past peritonitis was not associated with increased risk for postoperative complications in PD patients. Patient and graft survival were similar between PD and HD groups. Conclusions: Peritoneal dialysis is not a risk factor for postoperative complications after SPKT.
Subject: Kidney Transplantation
Pancreas Transplantation
Patient Outcome Assessment
Peritoneal Dialysis
Postoperative Complications
Renal Dialysis
IMPROVED PATIENT SURVIVAL
PERITONEAL-DIALYSIS
MORTALITY-RATES
RECIPIENTS
HEMODIALYSIS
IMPACT
ASSOCIATION
RISKS
3126 Surgery, anesthesiology, intensive care, radiology
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