The Older Finnish Twin Cohort-45 Years of Follow-up

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Kaprio , J , Bollepalli , S , Buchwald , J , Iso-Markku , P , Korhonen , T , Kovanen , V , Kujala , U , Laakkonen , E K , Latvala , A , Leskinen , T , Lindgren , N , Ollikainen , M , Piirtola , M , Rantanen , T , Rinne , J , Rose , R J , Sillanpää , E , Silventoinen , K , Sipilä , S , Viljanen , A , Vuoksimaa , E & Waller , K 2019 , ' The Older Finnish Twin Cohort-45 Years of Follow-up ' , Twin Research and Human Genetics , vol. 22 , no. 4 , 1832427419000549 , pp. 240-254 . https://doi.org/10.1017/thg.2019.54

Title: The Older Finnish Twin Cohort-45 Years of Follow-up
Author: Kaprio, Jaakko; Bollepalli, Sailalitha; Buchwald, Jadwiga; Iso-Markku, Paula; Korhonen, Tellervo; Kovanen, Vuokko; Kujala, Urho; Laakkonen, Eija K.; Latvala, Antti; Leskinen, Tuija; Lindgren, Noora; Ollikainen, Miina; Piirtola, Maarit; Rantanen, Taina; Rinne, Juha; Rose, Richard J.; Sillanpää, Elina; Silventoinen, Karri; Sipilä, Sarianna; Viljanen, Anne; Vuoksimaa, Eero; Waller, Katja
Contributor organization: Institute for Molecular Medicine Finland
Department of Public Health
University of Helsinki
HUS Medical Imaging Center
Department of Diagnostics and Therapeutics
University Management
Staff Services
Helsinki Inequality Initiative (INEQ)
Doctoral Programme in Social Sciences
Demography
Population Research Unit (PRU)
Center for Population, Health and Society
Sociology
Epigenetics of Complex Diseases and Traits
Genetic Epidemiology
Cognitive and Brain Aging
Date: 2019-08
Language: eng
Number of pages: 15
Belongs to series: Twin Research and Human Genetics
ISSN: 1832-4274
DOI: https://doi.org/10.1017/thg.2019.54
URI: http://hdl.handle.net/10138/306592
Abstract: The older Finnish Twin Cohort (FTC) was established in 1974. The baseline survey was in 1975, with two follow-up health surveys in 1981 and 1990. The fourth wave of assessments was done in three parts, with a questionnaire study of twins born during 1945-1957 in 2011-2012, while older twins were interviewed and screened for dementia in two time periods, between 1999 and 2007 for twins born before 1938 and between 2013 and 2017 for twins born in 1938-1944. The content of these wave 4 assessments is described and some initial results are described. In addition, we have invited twin-pairs, based on response to the cohortwide surveys, to participate in detailed in-person studies; these are described briefly together with key results. We also review other projects based on the older FTC and provide information on the biobanking of biosamples and related phenotypes.
Subject: Aging
alcohol
cohort study
dementia
epigenetics
hypertension
longitudinal
physical activity
review
smoking
twins
TIME PHYSICAL-ACTIVITY
HORMONE-REPLACEMENT THERAPY
GENOME-WIDE ASSOCIATION
POPULATION-BASED TWIN
SKELETAL-MUSCLE
PAIRS DISCORDANT
TELOMERE LENGTH
BLOOD-PRESSURE
ENVIRONMENTAL-INFLUENCES
DEPRESSIVE SYMPTOMS
1184 Genetics, developmental biology, physiology
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion


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