Dietary Fructose and the Metabolic Syndrome

Show full item record



Permalink

http://hdl.handle.net/10138/306760

Citation

Taskinen , M-R , Packard , C J & Boren , J 2019 , ' Dietary Fructose and the Metabolic Syndrome ' , Nutrients , vol. 11 , no. 9 , 1987 . https://doi.org/10.3390/nu11091987

Title: Dietary Fructose and the Metabolic Syndrome
Author: Taskinen, Marja-Riitta; Packard, Chris J.; Boren, Jan
Other contributor: University of Helsinki, HUS Heart and Lung Center




Date: 2019-09
Language: eng
Number of pages: 16
Belongs to series: Nutrients
ISSN: 2072-6643
DOI: https://doi.org/10.3390/nu11091987
URI: http://hdl.handle.net/10138/306760
Abstract: Consumption of fructose, the sweetest of all naturally occurring carbohydrates, has increased dramatically in the last 40 years and is today commonly used commercially in soft drinks, juice, and baked goods. These products comprise a large proportion of the modern diet, in particular in children, adolescents, and young adults. A large body of evidence associate consumption of fructose and other sugar-sweetened beverages with insulin resistance, intrahepatic lipid accumulation, and hypertriglyceridemia. In the long term, these risk factors may contribute to the development of type 2 diabetes and cardiovascular diseases. Fructose is absorbed in the small intestine and metabolized in the liver where it stimulates fructolysis, glycolysis, lipogenesis, and glucose production. This may result in hypertriglyceridemia and fatty liver. Therefore, understanding the mechanisms underlying intestinal and hepatic fructose metabolism is important. Here we review recent evidence linking excessive fructose consumption to health risk markers and development of components of the Metabolic Syndrome.
Subject: fructose
metabolic syndrome
hypertriglyceridemia
metabolism
FATTY LIVER-DISEASE
SERUM URIC-ACID
DE-NOVO LIPOGENESIS
SWEETENED BEVERAGES
INSULIN SENSITIVITY
HEPATIC STEATOSIS
CARDIOVASCULAR-DISEASE
CARDIOMETABOLIC HEALTH
INTRAHEPATIC LIPIDS
OXIDATIVE STRESS
3121 Internal medicine
3143 Nutrition
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
nutrients_11_01987_v2.pdf 1.278Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record