The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study

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Karamanakos , G , Costa-Pinel , B , Gilis-Januszewska , A , Velickiene , D , Barrio-Torrell , F , Cos-Claramunt , X , Mestre-Miravet , S , Piwońska-Solska , B , Hubalewska-Dydejczyk , A , Tuomilehto , J , Liatis , S & Makrilakis , K 2019 , ' The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study ' , PLoS One , vol. 14 , no. 10 , e0221467 . https://doi.org/10.1371/journal.pone.0221467

Title: The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study
Author: Karamanakos, Georgios; Costa-Pinel, Bernardo; Gilis-Januszewska, Aleksandra; Velickiene, Dzilda; Barrio-Torrell, Francisco; Cos-Claramunt, Xavier; Mestre-Miravet, Santiago; Piwońska-Solska, Beata; Hubalewska-Dydejczyk, Alicja; Tuomilehto, Jaakko; Liatis, Stavros; Makrilakis, Konstantinos
Contributor: University of Helsinki, Clinicum
Date: 2019-10-11
Language: eng
Number of pages: 17
Belongs to series: PLoS One
ISSN: 1932-6203
URI: http://hdl.handle.net/10138/306849
Abstract: Background and aims The DE-PLAN was a European multicenter study, with the primary objective of testing whether a community-based lifestyle modification programme could serve as a means of primary prevention for type 2 diabetes (T2D) in high-risk individuals (based on the FINDRISC questionnaire). The aim of this study was to examine the impact of a 1-year community-based lifestyle intervention on health-related quality of life (HRQOL) in individuals from four participating European centers (Athens, Barcelona, Krakow, Kaunas), through a post-hoc analysis. Materials and methods Each center was allowed to implement different intervention strategies specifically tailored to the needs of their corresponding population sample. Before and after the intervention, participants underwent clinical evaluation, anthropometric measurements, an oral glucose tolerance test and lipid profile measurements. Health-related quality of life was assessed using the validated HRQOL-15D questionnaire. A difference of ±0.015 in the 15D questionnaire score was set as the threshold of clinically meaningful change. Results Data from 786 participants (67% females, mean age 59.7±9.4 years, BMI 31.5±4.5 kg/m2) with complete data regarding the HRQOL were analyzed (Athens: 104, Barcelona: 434, Krakow: 175, Kaunas: 70). After 1 year, a significant overall improvement in HRQOL was shown, as depicted by a change of 15D score from baseline value (0.88±0.9) to post-intervention (0.90±0.87, P
Subject: 3142 Public health care science, environmental and occupational health
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