The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study

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dc.contributor University of Helsinki, Clinicum en
dc.contributor.author Karamanakos, Georgios
dc.contributor.author Costa-Pinel, Bernardo
dc.contributor.author Gilis-Januszewska, Aleksandra
dc.contributor.author Velickiene, Dzilda
dc.contributor.author Barrio-Torrell, Francisco
dc.contributor.author Cos-Claramunt, Xavier
dc.contributor.author Mestre-Miravet, Santiago
dc.contributor.author Piwońska-Solska, Beata
dc.contributor.author Hubalewska-Dydejczyk, Alicja
dc.contributor.author Tuomilehto, Jaakko
dc.contributor.author Liatis, Stavros
dc.contributor.author Makrilakis, Konstantinos
dc.date.accessioned 2019-11-11T07:53:01Z
dc.date.available 2019-11-11T07:53:01Z
dc.date.issued 2019-10-11
dc.identifier.citation Karamanakos , G , Costa-Pinel , B , Gilis-Januszewska , A , Velickiene , D , Barrio-Torrell , F , Cos-Claramunt , X , Mestre-Miravet , S , Piwońska-Solska , B , Hubalewska-Dydejczyk , A , Tuomilehto , J , Liatis , S & Makrilakis , K 2019 , ' The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study ' , PLoS One , vol. 14 , no. 10 , e0221467 . https://doi.org/10.1371/journal.pone.0221467 en
dc.identifier.issn 1932-6203
dc.identifier.other PURE: 127478780
dc.identifier.other PURE UUID: 24949782-66ef-41ff-a48b-65ac577505e2
dc.identifier.other RIS: urn:5F0256009AF07027B5D3FD69BC1C6481
dc.identifier.other WOS: 000532477400003
dc.identifier.uri http://hdl.handle.net/10138/306849
dc.description.abstract Background and aims The DE-PLAN was a European multicenter study, with the primary objective of testing whether a community-based lifestyle modification programme could serve as a means of primary prevention for type 2 diabetes (T2D) in high-risk individuals (based on the FINDRISC questionnaire). The aim of this study was to examine the impact of a 1-year community-based lifestyle intervention on health-related quality of life (HRQOL) in individuals from four participating European centers (Athens, Barcelona, Krakow, Kaunas), through a post-hoc analysis. Materials and methods Each center was allowed to implement different intervention strategies specifically tailored to the needs of their corresponding population sample. Before and after the intervention, participants underwent clinical evaluation, anthropometric measurements, an oral glucose tolerance test and lipid profile measurements. Health-related quality of life was assessed using the validated HRQOL-15D questionnaire. A difference of ±0.015 in the 15D questionnaire score was set as the threshold of clinically meaningful change. Results Data from 786 participants (67% females, mean age 59.7±9.4 years, BMI 31.5±4.5 kg/m2) with complete data regarding the HRQOL were analyzed (Athens: 104, Barcelona: 434, Krakow: 175, Kaunas: 70). After 1 year, a significant overall improvement in HRQOL was shown, as depicted by a change of 15D score from baseline value (0.88±0.9) to post-intervention (0.90±0.87, P en
dc.format.extent 17
dc.language.iso eng
dc.relation.ispartof PLoS One
dc.rights en
dc.subject 3142 Public health care science, environmental and occupational health en
dc.title The effectiveness of a community-based, type 2 diabetes prevention programme on health-related quality of life. The DE-PLAN study en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1371/journal.pone.0221467
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
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