Role of inflammation markers in the prediction of weight gain and development of obesity in adults – a prospective study

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dc.contributor University of Helsinki, Department of Public Health en
dc.contributor University of Helsinki, Staff Services en
dc.contributor.author Tuomisto, K.
dc.contributor.author Jousilahti, P.
dc.contributor.author Havulinna, A.S.
dc.contributor.author Borodulin, K.
dc.contributor.author Männistö, S.
dc.contributor.author Salomaa, V.
dc.date.accessioned 2019-11-11T09:25:01Z
dc.date.available 2019-11-11T09:25:01Z
dc.date.issued 2019-08-27
dc.identifier.citation Tuomisto , K , Jousilahti , P , Havulinna , A S , Borodulin , K , Männistö , S & Salomaa , V 2019 , ' Role of inflammation markers in the prediction of weight gain and development of obesity in adults – a prospective study ' , Metabolism open , vol. 3 , 100016 . https://doi.org/10.1016/j.metop.2019.100016 en
dc.identifier.issn 2589-9368
dc.identifier.other PURE: 126504433
dc.identifier.other PURE UUID: 274c1efc-816d-4ee9-a7e6-4937602545a9
dc.identifier.other RIS: urn:DBA88AC513380F80DA1D4FCC382D3A27
dc.identifier.uri http://hdl.handle.net/10138/306860
dc.description.abstract BACKGROUND AND AIMS There is a growing body of literature confirming the association between inflammation and obesity. Recent research suggests that inflammation may play a role in weight gain. The aim of the study was to analyse whether serum inflammatory markers predict weight gain or development of obesity in a prospective study design. METHODS AND RESULTS The baseline study (DILGOM 2007) consists of a population-based sample of 5024 Finnish men and women aged 25-75 years, of whom 3735 participated in the follow-up study in 2014. Baseline data collection included a questionnaire on health behaviour, physical examinations and blood samples including serum high-sensitivity C-Reactive Protein (hs-CRP), Interleukin-1 receptor antagonist (IL-1Ra), Interleukin-6 (IL-6), Tumor Necrosis Factor Alpha (TNF-alpha) and high molecular weight adiponectin (HMW adiponectin). Indicators of obesity were weight, body mass index (BMI), waist circumference and body fat percentage (% body fat). At baseline hs-CRP, IL-1Ra, IL-6, TNF-alpha and HMW adiponectin associated strongly (p en
dc.format.extent 6
dc.language.iso eng
dc.relation.ispartof Metabolism open
dc.rights en
dc.subject Inflammation en
dc.subject Obesity en
dc.subject Weight gain en
dc.subject Epidemiology en
dc.subject 3111 Biomedicine en
dc.subject 3121 General medicine, internal medicine and other clinical medicine en
dc.title Role of inflammation markers in the prediction of weight gain and development of obesity in adults – a prospective study en
dc.type Article
dc.description.version Peer reviewed
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1016/j.metop.2019.100016
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/acceptedVersion
dc.type.uri info:eu-repo/semantics/publishedVersion
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