Lipidomics in biomedical research-practical considerations

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http://hdl.handle.net/10138/307577

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Hyotylainen , T , Ahonen , L , Pöhö , P & Oresic , M 2017 , ' Lipidomics in biomedical research-practical considerations ' , Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids , vol. 1862 , no. 8 , pp. 800-803 . https://doi.org/10.1016/j.bbalip.2017.04.002

Title: Lipidomics in biomedical research-practical considerations
Author: Hyotylainen, Tuulia; Ahonen, Linda; Pöhö, Paivi; Oresic, Matej
Contributor: University of Helsinki, Faculty of Pharmacy
Date: 2017-08
Language: eng
Number of pages: 4
Belongs to series: Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids
ISSN: 1388-1981
URI: http://hdl.handle.net/10138/307577
Abstract: Lipids have many central physiological roles including as structural components of cell membranes, energy storage sources and intermediates in signaling pathways. Lipid-related disturbances are known to underlie many diseases and their co-morbidities. The emergence of lipidomics has empowered researchers to study lipid metabolism at the cellular as well as physiological levels at a greater depth than was previously possible. The key challenges ahead in the field of lipidomics in medical research lie in the development of experimental protocols and in silico techniques needed to study lipidomes at the systems level. Clinical questions where lipidomics may have an impact in healthcare settings also need to be identified, both from the health outcomes and health economics perspectives. This article is part of a Special Issue entitled: BBALIP_Lipidomics Opinion Articles edited by Sepp Kohlwein.
Subject: Biomarkers
Data processing
Lipidomics
Mass spectrometry
Metabolomics
Quality control
MOLECULAR PROFILE DATA
FATTY-LIVER-DISEASE
MASS-SPECTROMETRY
METABOLOMICS DATA
SYSTEMS BIOLOGY
BLOOD-PLASMA
GENOME-SCALE
EXTRACTION
SERUM
METABOLISM
1182 Biochemistry, cell and molecular biology
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