Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington’s disease

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Norrbacka , S , Lindholm , D & Myöhänen , T T 2019 , ' Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington’s disease ' , Journal of Cellular and Molecular Medicine , vol. 23 , no. 12 , pp. 8511-8515 . https://doi.org/10.1111/jcmm.14675

Title: Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington’s disease
Author: Norrbacka, Susanna; Lindholm, Dan; Myöhänen, Timo T.
Contributor: University of Helsinki, Division of Pharmacology and Pharmacotherapy
University of Helsinki, Department of Biochemistry and Developmental Biology
University of Helsinki, Faculty of Pharmacy
Date: 2019-12
Language: eng
Number of pages: 5
Belongs to series: Journal of Cellular and Molecular Medicine
ISSN: 1582-1838
URI: http://hdl.handle.net/10138/307592
Subject: autophagy
huntingtin
neurodegeneration
protein aggregation
protein processing
ALPHA-SYNUCLEIN
INVOLVEMENT
PARKINSONS
PROTEASOME
AUTOPHAGY
KYP-2047
PROTEIN
DRUG
1182 Biochemistry, cell and molecular biology
3111 Biomedicine
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