Non-curative treatment of patients with oral tongue squamous-cell carcinoma

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http://hdl.handle.net/10138/308432

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Mroueh , R , Haapaniemi , A , Saarto , T , Grönholm , L , Grénman , R , Salo , T & Mäkitie , A A 2019 , ' Non-curative treatment of patients with oral tongue squamous-cell carcinoma ' , European Archives of Oto-Rhino-Laryngology , vol. 276 , no. 7 , pp. 2039-2045 . https://doi.org/10.1007/s00405-019-05456-y

Title: Non-curative treatment of patients with oral tongue squamous-cell carcinoma
Author: Mroueh, R.; Haapaniemi, A.; Saarto, T.; Grönholm, L.; Grénman, R.; Salo, T.; Mäkitie, A. A.
Other contributor: University of Helsinki, Department of Oral and Maxillofacial Diseases
University of Helsinki, Department of Ophthalmology and Otorhinolaryngology
University of Helsinki, Department of Oncology
University of Helsinki, HUS Comprehensive Cancer Center
University of Helsinki, Department of Oral and Maxillofacial Diseases
University of Helsinki, Department of Ophthalmology and Otorhinolaryngology








Date: 2019-07
Language: eng
Number of pages: 7
Belongs to series: European Archives of Oto-Rhino-Laryngology
ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-019-05456-y
URI: http://hdl.handle.net/10138/308432
Abstract: PurposeLate-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival.MethodsAll patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005-2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan-Meier method in this population-based study.ResultsEighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7months (median 2 and range 0-26).ConclusionsDue to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted.
Subject: 3122 Cancers
Head and neck cancer
Tongue cancer
Palliative care
Palliation
Surgery
Chemotherapy
End of life
Quality of life
Death
PERCUTANEOUS ENDOSCOPIC GASTROSTOMY
PALLIATIVE CARE
CANCER-PATIENTS
NECK-CANCER
HEAD
RADIOTHERAPY
SURVIVAL
CISPLATIN
DOCETAXEL
REFUSAL
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