Non-curative treatment of patients with oral tongue squamous-cell carcinoma
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Mroueh , R , Haapaniemi , A , Saarto , T , Grönholm , L , Grénman , R , Salo , T & Mäkitie , A A 2019 , ' Non-curative treatment of patients with oral tongue squamous-cell carcinoma ' , European Archives of Oto-Rhino-Laryngology , vol. 276 , no. 7 , pp. 2039-2045 . https://doi.org/10.1007/s00405-019-05456-y
| Title: | Non-curative treatment of patients with oral tongue squamous-cell carcinoma |
| Author: | Mroueh, R.; Haapaniemi, A.; Saarto, T.; Grönholm, L.; Grénman, R.; Salo, T.; Mäkitie, A. A. |
| Contributor organization: | Department of Oral and Maxillofacial Diseases Clinicum HUS Head and Neck Center Department of Ophthalmology and Otorhinolaryngology Department of Surgery Department of Oncology University Management HUS Comprehensive Cancer Center HUSLAB |
| Date: | 2019-07 |
| Language: | eng |
| Number of pages: | 7 |
| Belongs to series: | European Archives of Oto-Rhino-Laryngology |
| ISSN: | 1434-4726 |
| DOI: | https://doi.org/10.1007/s00405-019-05456-y |
| URI: | http://hdl.handle.net/10138/308432 |
| Abstract: | PurposeLate-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival.MethodsAll patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005-2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan-Meier method in this population-based study.ResultsEighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7months (median 2 and range 0-26).ConclusionsDue to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted. |
| Subject: |
3122 Cancers
Head and neck cancer Tongue cancer Palliative care Palliation Surgery Chemotherapy End of life Quality of life Death PERCUTANEOUS ENDOSCOPIC GASTROSTOMY PALLIATIVE CARE CANCER-PATIENTS NECK-CANCER HEAD RADIOTHERAPY SURVIVAL CISPLATIN DOCETAXEL REFUSAL |
| Peer reviewed: | Yes |
| Rights: | cc_by |
| Usage restriction: | openAccess |
| Self-archived version: | publishedVersion |
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