Treatment of Ruptured Intracranial Aneurysms Using the Woven EndoBridge Device : A Two-Center Experience

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http://hdl.handle.net/10138/308541

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Raj , R , Rautio , R , Pekkola , J , Rahi , M , Sillanpää , M & Numminen , J 2019 , ' Treatment of Ruptured Intracranial Aneurysms Using the Woven EndoBridge Device : A Two-Center Experience ' , World Neurosurgery , vol. 123 , pp. E709-E716 . https://doi.org/10.1016/j.wneu.2018.12.010

Title: Treatment of Ruptured Intracranial Aneurysms Using the Woven EndoBridge Device : A Two-Center Experience
Author: Raj, Rahul; Rautio, Riitta; Pekkola, Johanna; Rahi, Melissa; Sillanpää, Mikko; Numminen, Jussi
Contributor: University of Helsinki, HUS Neurocenter
University of Helsinki, Department of Diagnostics and Therapeutics
University of Helsinki, Mikko Sillanpää / Principal Investigator
University of Helsinki, Department of Diagnostics and Therapeutics
Date: 2019-03
Language: eng
Number of pages: 8
Belongs to series: World Neurosurgery
ISSN: 1878-8750
URI: http://hdl.handle.net/10138/308541
Abstract: BACKGROUND: The Woven EndoBridge (WEB) device is a new treatment modality developed for broad-necked unruptured intracranial aneurysms (IAs) but shows potential for the treatment of ruptured IAs as well. Our aim was to describe 6-month aneurysm obliteration rates, clinical outcomes, and procedure-related complications after WEB treatment for ruptured IAs from 2 academic centers. METHODS: We conducted a retrospective observational study, including all consecutive patients treated with the WEB device (WEB single layer and single-layer sphere) for a ruptured IA causing acute subarachnoid hemorrhage between 2014 (start of use) and 2017. Primary outcome was angiographic aneurysm obliteration (Beaujon Occlusion Scale Score) rate. Secondary outcomes were early re-bleedings, complications, and patient outcome (death and modified Rankin Scale). RESULTS: A total of 33 patients with ruptured IAs were treated 0-4 days from IA rupture. Of 27 survivors, 6-month angiographic follow-up was available for 26 patients, of whom 81% showed complete occlusion. Of the 27 survivors, 24 patients (89%) had a favorable neurologic outcome at 6 months after subarachnoid hemorrhage. Two aneurysms were retreated (8% of all). There was 1 fatal procedure-related complication. No early aneurysm re-bleedings were noted. CONCLUSIONS: For anatomically suitable ruptured IAs, WEB device treatment seems to be safe and results in acceptable occlusion rates. Still, larger studies with long-term results are needed before recommendations can be made.
Subject: Intracranial aneurysm
Stroke
Subarachnoid hemorrhage
WEB
Woven EndoBridge device
INTRASACCULAR FLOW-DISRUPTION
CEREBRAL ANEURYSMS
WEB TREATMENT
ENDOVASCULAR TREATMENT
COIL EMBOLIZATION
TRIAL
COMPLICATIONS
FEASIBILITY
RETREATMENT
COHORT
3112 Neurosciences
3124 Neurology and psychiatry
3126 Surgery, anesthesiology, intensive care, radiology
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