Anti-Ascaris suum IgG antibodies in fattening pigs with different respiratory conditions

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dc.contributor.author Lassen, Brian
dc.contributor.author Geldhof, Peter
dc.contributor.author Hälli, Outi
dc.contributor.author Vlaminck, Johnny
dc.contributor.author Oliviero, Claudio
dc.contributor.author Orro, Toomas
dc.contributor.author Heinonen, Mari
dc.date.accessioned 2019-12-19T23:01:40Z
dc.date.available 2021-12-17T22:45:27Z
dc.date.issued 2019-01
dc.identifier.citation Lassen , B , Geldhof , P , Hälli , O , Vlaminck , J , Oliviero , C , Orro , T & Heinonen , M 2019 , ' Anti-Ascaris suum IgG antibodies in fattening pigs with different respiratory conditions ' , Veterinary Parasitology , vol. 265 , pp. 85-90 . https://doi.org/10.1016/j.vetpar.2018.12.005
dc.identifier.other PURE: 122777986
dc.identifier.other PURE UUID: c742a267-7a6b-49dd-9159-b1d947526914
dc.identifier.other WOS: 000458595500012
dc.identifier.other Scopus: 85058648448
dc.identifier.other ORCID: /0000-0002-5732-0692/work/54789918
dc.identifier.other ORCID: /0000-0001-8910-9595/work/86096025
dc.identifier.uri http://hdl.handle.net/10138/308653
dc.description.abstract During their migration through the pig's body, Ascaris suum larvae cause significant damage to the lungs. Little is known about the actual impact of this tissue damage on the occurrence and severity of respiratory problems in industrial pig fattening farms. In this study, we evaluated the link between the serological response to two different A. suum antigen preparations and respiratory or meat inspection outcomes. Two different serological tests were used that measure antibodies against either the A. suum haemoglobin molecule or complete homogenate of the 3rd stage larva that migrate through the lungs. Firstly, serum samples were analysed that were collected from 19 herds in which the cause of acute clinical respiratory symptoms was either Actinobacillus pleuropneumoniae, A. suum, or a miscellaneous cause. This was done to test whether serological results could confirm pathological findings. Secondly, serum samples from 60 herds of finishing pigs with a history of high or low frequency of pleuritis at meat inspection (MI), but without acute respiratory symptoms at the time of sampling, were also submitted for serological evaluation using both tests. Regression models were used to search for potential associations between the proportion of pigs testing seropositive with MI results, in particular pathological changes related to the lungs. The results of both ELISAs were strongly associated (P <0.001) with pigs belonging to a herd where the respiratory problems could be attributed to A. swim by histology, indicating that both tests can be used to diagnose clinical respiratory outbreaks due to A. suum. In the herds without acute clinical respiratory symptoms, a positive association was found between the proportion of pigs testing seropositive and the percentage of livers rejected due to milk spots and with whole carcass condemnations. No association was found between Ascaris serology and lung pathology (pneumonia and pleuritis) registered at MI, however, challenging the likely involvement of Ascaris in the development of these lesions. en
dc.format.extent 6
dc.language.iso eng
dc.relation.ispartof Veterinary Parasitology
dc.rights cc_by_nc_nd
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Helminth
dc.subject Swine
dc.subject Pleuritis
dc.subject Pneumonia
dc.subject Respiratory
dc.subject Farm
dc.subject Meat inspection
dc.subject LARVAL MIGRATION
dc.subject INFECTIONS
dc.subject SWINE
dc.subject PERFORMANCE
dc.subject DISEASES
dc.subject 413 Veterinary science
dc.subject 1183 Plant biology, microbiology, virology
dc.title Anti-Ascaris suum IgG antibodies in fattening pigs with different respiratory conditions en
dc.type Article
dc.contributor.organization Departments of Faculty of Veterinary Medicine
dc.contributor.organization Production Animal Medicine
dc.contributor.organization Faculty of Veterinary Medicine
dc.contributor.organization Mari Heinonen / Principal Investigator
dc.contributor.organization Research Centre for Animal Welfare
dc.contributor.organization Helsinki One Health (HOH)
dc.contributor.organization Animal Reproduction Science
dc.contributor.organization Teachers' Academy
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.vetpar.2018.12.005
dc.relation.issn 0304-4017
dc.rights.accesslevel openAccess
dc.type.version acceptedVersion

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