A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus

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dc.contributor.author Farmakis, Dimitrios
dc.contributor.author Agostoni, Piergiuseppe
dc.contributor.author Baholli, Loant
dc.contributor.author Bautin, Andrei
dc.contributor.author Comin-Colet, Josep
dc.contributor.author Crespo-Leiro, Maria G.
dc.contributor.author Fedele, Francesco
dc.contributor.author García-Pinilla, Jose Manuel
dc.contributor.author Giannakoulas, George
dc.contributor.author Grigioni, Francesco
dc.contributor.author Gruchała, Marcin
dc.contributor.author Gustafsson, Finn
dc.contributor.author Harjola, Veli-Pekka
dc.contributor.author Hasin, Tal
dc.contributor.author Herpain, Antoine
dc.contributor.author Iliodromitis, Efstathios K.
dc.contributor.author Karason, Kristjan
dc.contributor.author Kivikko, Matti
dc.contributor.author Liaudet, Lucas
dc.contributor.author Ljubas-Maček, Jana
dc.contributor.author Marini, Marco
dc.contributor.author Masip, Josep
dc.contributor.author Mebazaa, Alexandre
dc.contributor.author Nikolaou, Maria
dc.contributor.author Ostadal, Petr
dc.contributor.author Põder, Pentti
dc.contributor.author Pollesello, Piero
dc.contributor.author Polyzogopoulou, Eftihia
dc.contributor.author Pölzl, Gerhard
dc.contributor.author Tschope, Carsten
dc.contributor.author Varpula, Marjut
dc.contributor.author von Lewinski, Dirk
dc.contributor.author Vrtovec, Bojan
dc.contributor.author Yilmaz, Mehmet Birhan
dc.contributor.author Zima, Endre
dc.contributor.author Parissis, John
dc.date.accessioned 2020-01-10T13:07:01Z
dc.date.available 2020-01-10T13:07:01Z
dc.date.issued 2019-12-15
dc.identifier.citation Farmakis , D , Agostoni , P , Baholli , L , Bautin , A , Comin-Colet , J , Crespo-Leiro , M G , Fedele , F , García-Pinilla , J M , Giannakoulas , G , Grigioni , F , Gruchała , M , Gustafsson , F , Harjola , V-P , Hasin , T , Herpain , A , Iliodromitis , E K , Karason , K , Kivikko , M , Liaudet , L , Ljubas-Maček , J , Marini , M , Masip , J , Mebazaa , A , Nikolaou , M , Ostadal , P , Põder , P , Pollesello , P , Polyzogopoulou , E , Pölzl , G , Tschope , C , Varpula , M , von Lewinski , D , Vrtovec , B , Yilmaz , M B , Zima , E & Parissis , J 2019 , ' A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus ' , International Journal of Cardiology , vol. 297 , pp. 83-90 . https://doi.org/10.1016/j.ijcard.2019.09.005
dc.identifier.other PURE: 126671042
dc.identifier.other PURE UUID: 100571b2-43ec-4dbf-8285-89c8222dfc02
dc.identifier.other RIS: urn:9792FDC5E741C6AECFC6164EDF9D7F8D
dc.identifier.other WOS: 000502550800019
dc.identifier.uri http://hdl.handle.net/10138/309256
dc.description.abstract Inotropes aim at increasing cardiac output by enhancing cardiac contractility. They constitute the third pharmacological pillar in the treatment of patients with decompensated heart failure, the other two being diuretics and vasodilators. Three classes of parenterally administered inotropes are currently indicated for decompensated heart failure, (i) the beta adrenergic agonists, including dopamine and dobutamine and also the catecholamines epinephrine and norepinephrine, (ii) the phosphodiesterase III inhibitor milrinone and (iii) the calcium sensitizer levosimendan. These three families of drugs share some pharmacologic traits, but differ profoundly in many of their pleiotropic effects. Identifying the patients in need of inotropic support and selecting the proper inotrope in each case remain challenging. The present consensus, derived by a panel meeting of experts from 21 countries, aims at addressing this very issue in the setting of both acute and advanced heart failure. (C) 2019 The Authors. Published by Elsevier B.V. en
dc.format.extent 8
dc.language.iso eng
dc.relation.ispartof International Journal of Cardiology
dc.rights cc_by_nc_nd
dc.rights cc_by_nc_nd
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.subject Acute heart failure
dc.subject Advanced heart failure
dc.subject Inotropes
dc.subject Inodilators
dc.subject Levosimendan
dc.subject Dobutamine
dc.subject Milrinone
dc.subject Norepinephrine
dc.subject LONG-TERM
dc.subject MORTALITY
dc.subject INTERMITTENT LEVOSIMENDAN TREATMENT
dc.subject MILRINONE
dc.subject CLINICAL CHARACTERISTICS
dc.subject SYSTOLIC FUNCTION
dc.subject REPETITIVE USE
dc.subject CARDIOGENIC-SHOCK
dc.subject INFUSIONS
dc.subject QUALITY-OF-LIFE
dc.title A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus en
dc.type Article
dc.contributor.organization HUS Emergency Medicine and Services
dc.contributor.organization Department of Diagnostics and Therapeutics
dc.contributor.organization University of Helsinki
dc.contributor.organization HUS Internal Medicine and Rehabilitation
dc.contributor.organization HUS Heart and Lung Center
dc.contributor.organization Kardiologian yksikkö
dc.contributor.organization Department of Medicine
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.ijcard.2019.09.005
dc.relation.issn 0167-5273
dc.rights.accesslevel openAccess
dc.type.version acceptedVersion
dc.type.version publishedVersion

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