Estimation of inbreeding depression on female fertility in the Finnish Ayrshire population

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http://hdl.handle.net/10138/309588

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Martikainen , K , Tyrisevä , A M , Matilainen , K , Pösö , J & Uimari , P 2017 , ' Estimation of inbreeding depression on female fertility in the Finnish Ayrshire population ' , Journal of Animal Breeding and Genetics , vol. 134 , no. 5 , pp. 383-392 . https://doi.org/10.1111/jbg.12285

Title: Estimation of inbreeding depression on female fertility in the Finnish Ayrshire population
Author: Martikainen, K.; Tyrisevä, A. M.; Matilainen, K.; Pösö, J.; Uimari, P.
Contributor organization: University of Helsinki
Department of Agricultural Sciences
Animal Science Research
Date: 2017-10
Language: eng
Number of pages: 10
Belongs to series: Journal of Animal Breeding and Genetics
ISSN: 0931-2668
DOI: https://doi.org/10.1111/jbg.12285
URI: http://hdl.handle.net/10138/309588
Abstract: Single nucleotide polymorphism (SNP) data enable the estimation of inbreeding at the genome level. In this study, we estimated inbreeding levels for 19,075 Finnish Ayrshire cows genotyped with a low-density SNP panel (8K). The genotypes were imputed to 50K density, and after quality control, 39,144 SNPs remained for the analysis. Inbreeding coefficients were estimated for each animal based on the percentage of homozygous SNPs (F-PH), runs of homozygosity (F-ROH) and pedigree (F-PED). Phenotypic records were available for 13,712 animals including non-return rate (NRR), number of inseminations (AIS) and interval from first to last insemination (IFL) for heifers and up to three parities for cows, as well as interval from calving to first insemination (ICF) for cows. Average F-PED was 0.02, F-ROH 0.06 and F-PH 0.63. A correlation of 0.71 was found between F-PED and F-ROH, 0.66 between F-PED and F-PH and 0.94 between F-ROH and F-PH. Pedigree-based inbreeding coefficients did not show inbreeding depression in any of the traits. However, when F-ROH or F-PH was used as a covariate, significant inbreeding depression was observed; a 10% increase in F-ROH was associated with 5days longer IFL0 and IFL1, 2weeks longer IFL3 and 3days longer ICF2 compared to non-inbred cows.
Subject: cattle
fertility
inbreeding
inbreeding depression
runs of homozygosity
SNP
DAIRY-CATTLE
HOLSTEIN
PERFORMANCE
PEDIGREE
JERSEYS
TRAITS
412 Animal science, dairy science
Peer reviewed: Yes
Rights: unspecified
Usage restriction: openAccess
Self-archived version: acceptedVersion


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