Summanen , M , Seikku , L , Rahkonen , P , Stefanovic , V , Teramo , K , Andersson , S , Kaila , K & Rahkonen , L 2017 , ' Comparison of Umbilical Serum Copeptin Relative to Erythropoietin and S100B as Asphyxia Biomarkers at Birth ' , Neonatology , vol. 112 , no. 1 , pp. 60-66 . https://doi.org/10.1159/000456063
Title: | Comparison of Umbilical Serum Copeptin Relative to Erythropoietin and S100B as Asphyxia Biomarkers at Birth |
Author: | Summanen, Milla; Seikku, Laura; Rahkonen, Petri; Stefanovic, Vedran; Teramo, Kari; Andersson, Sture; Kaila, Kai; Rahkonen, Leena |
Contributor organization: | Laboratory of Neurobiology University of Helsinki Biosciences Neuroscience Center Helsinki Institute of Life Science HiLIFE Department of Obstetrics and Gynecology HUS Gynecology and Obstetrics HUS Children and Adolescents Children's Hospital Clinicum Kai Kaila / Principal Investigator Physiology and Neuroscience (-2020) |
Date: | 2017 |
Language: | eng |
Number of pages: | 7 |
Belongs to series: | Neonatology |
ISSN: | 1661-7800 |
DOI: | https://doi.org/10.1159/000456063 |
URI: | http://hdl.handle.net/10138/310867 |
Abstract: | Background: Birth asphyxia, estimated to account for a million neonatal deaths annually, can cause a wide variety of neurodevelopmental impairments. There is a need to develop new, swift methods to identify those neonates who would benefit from neuroprotective treatments such as hypothermia. Objectives: To examine the utility of cord serum copeptin, a stable byproduct of arginine vasopressin release, as a biomarker of birth asphyxia based on a comparison with 2 biomarkers of hypoxia and brain trauma: erythropoietin and S100B. Methods: The study population consisted of 140 singleton, term neonates: 113 controls and 27 with birth asphyxia (2/3 criteria met: umbilical artery pH |
Subject: |
Neonate
Birth asphyxia Arginine vasopressin Copeptin Erythropoietin S100B AMNIOTIC-FLUID ERYTHROPOIETIN PLASMA COPEPTIN BRAIN-DAMAGE CORD BLOOD VASOPRESSIN INFANTS ENCEPHALOPATHY FETAL 3111 Biomedicine |
Peer reviewed: | Yes |
Usage restriction: | openAccess |
Self-archived version: | acceptedVersion |
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