Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Orebro County, Sweden, May 2019

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Unemo , M , Hansen , M , Hadad , R , Lindroth , Y , Fredlund , H , Puolakkainen , M & Sundqvist , M 2019 , ' Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Orebro County, Sweden, May 2019 ' , Eurosurveillance , vol. 24 , no. 26 , 1900370 , pp. 10-14 . https://doi.org/10.2807/1560-7917.ES.2019.24.26.1900370

Title: Finnish new variant of Chlamydia trachomatis escaping detection in the Aptima Combo 2 assay also present in Orebro County, Sweden, May 2019
Author: Unemo, Magnus; Hansen, Marit; Hadad, Ronza; Lindroth, Ylva; Fredlund, Hans; Puolakkainen, Mirja; Sundqvist, Martin
Contributor: University of Helsinki, HUSLAB
Date: 2019-06-27
Language: eng
Number of pages: 5
Belongs to series: Eurosurveillance
ISSN: 1560-7917
URI: http://hdl.handle.net/10138/311326
Abstract: We identified the first two cases of the Finnish new variant of Chlamydia trachomatis (F-nvCT) beyond Finland in two clinical urogenital specimens in Orebro County, Sweden. These Aptima Combo 2 assay-negative specimens were Aptima Chlamydia trachomatis (CT) assay positive and had the characteristic C1515T mutation in the 23S rRNA gene. From 22 March to 31 May 2019, 1.3% (2/158) of the CT-positive cases in Orebro County were missed because of the F-nvCT. International awareness, investigations and actions are essential.
Subject: SWEDISH
3111 Biomedicine
1183 Plant biology, microbiology, virology
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