Outcome of transition phase patients with juvenile idiopathic arthritis

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Relas , H , Luosujarvi , R & Kosola , S 2018 , ' Outcome of transition phase patients with juvenile idiopathic arthritis ' , Modern Rheumatology , vol. 28 , no. 5 , pp. 832-837 . https://doi.org/10.1080/14397595.2017.1416890

Title: Outcome of transition phase patients with juvenile idiopathic arthritis
Author: Relas, Heikki; Luosujarvi, Riitta; Kosola, Silja
Contributor organization: Reumatologian yksikkö
Department of Medicine
Children's Hospital
Lastentautien yksikkö
HUS Children and Adolescents
HUS Inflammation Center
Date: 2018
Language: eng
Number of pages: 6
Belongs to series: Modern Rheumatology
ISSN: 1439-7595
DOI: https://doi.org/10.1080/14397595.2017.1416890
URI: http://hdl.handle.net/10138/311366
Abstract: Objectives: Across diagnosis groups, successful transition of adolescent and young adults from children's hospitals to adult care is often associated with decreased treatment adherence and treatment results. The aim of this study was to characterize disease activity and anti-rheumatic medications following transfer of care of juvenile idiopathic arthritis (JIA) patients to the adult clinic.Method: All consecutive JIA patients aged 16-20 years who visited the specific transition clinic in the rheumatology outpatient clinic of Helsinki University Hospital between November 2012 and May 2013 and between April 2015 and April 2016 were evaluated.Results: A total of 214 patients were identified, and 23 appeared in both cohorts. Females had higher disease activity scores (DAS) than males (DAS28-CRP 1.90.7 versus 1.6 +/- 0.3, p=.019; and DAS44-CRP 1.0 +/- 0.7 versus 0.7 +/- 0.5, p=.005; respectively) in the latter cohort. Disease-modifying antirheumatic drugs (DMARDs) were prescribed to 86% of patients, and 48% were on biological DMARDs (bDMARDs), whereas 14% had no specific treatments.Conclusion: Disease activity and clinic attendance remained stable during the transition period. The proportion of transition phase JIA patients on bDMARDs was high and disease activity was low. Reasons for lower disease activity in males in the latter cohort require further investigation.
Subject: Adolescents
juvenile idiophatic arthritis
disease-modifying antirheumatic drugs
transition of care
3121 General medicine, internal medicine and other clinical medicine
3123 Gynaecology and paediatrics
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: acceptedVersion

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