Assessment of sedation level for endoscopic retrograde cholangiopancreatography - a prospective validation study

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Jokelainen , J , Mustonen , H , Kylänpää , L , Udd , M , Lindström , O & Pöyhiä , R 2018 , ' Assessment of sedation level for endoscopic retrograde cholangiopancreatography - a prospective validation study ' , Scandinavian Journal of Gastroenterology , vol. 53 , no. 3 , pp. 370-375 . https://doi.org/10.1080/00365521.2018.1435715

Title: Assessment of sedation level for endoscopic retrograde cholangiopancreatography - a prospective validation study
Author: Jokelainen, Jarno; Mustonen, Harri; Kylänpää, Leena; Udd, Marianne; Lindström, Outi; Pöyhiä, Reino
Contributor: University of Helsinki, HYKS erva
University of Helsinki, Clinicum
University of Helsinki, Department of Surgery
University of Helsinki, Clinicum
University of Helsinki, University of Helsinki
University of Helsinki, Clinicum
Date: 2018
Language: eng
Number of pages: 6
Belongs to series: Scandinavian Journal of Gastroenterology
ISSN: 0036-5521
URI: http://hdl.handle.net/10138/311385
Abstract: Background and aims: There is no consensus on how to assess the depth of sedation for endoscopic retrograde cholangiopancreatography (ERCP). This study was carried out in order to evaluate different methods of assessment of depth of sedation: bispectral index (BiS), modified Richmond Agitation/Sedation Scale (mRASS), modified Ramsay Sedation Scale (mRSS) and modified Observer Assessment of Alertness and Sedation (mOAAS) and their applicability to clinical practice.Methods: Two hundred patients were recruited. Sedation was given by standard clinical practice using propofol sedation or patient controlled sedation. Sedation was assessed on all patients using the above-mentioned methods. BiS was considered the reference point for sedation scales. Cronbach's alpha was calculated to determine the consistency of different scales in respect to each other and prediction probability and Spearman's correlation coefficients of sedation scales were calculated to show the relationship between sedation scales and BiS.Results: All scales showed high reliability with overall Cronbach's alpha 0.943. Dropping scales suggested better consistency between mOAAS, mRSS and mRASS than with BiS. Spearman's correlation and prediction probability showed similar results with all tested scales: mOAAS (0.695, 0.739), mRSS (0.673, 0.735), mRASS (0.683, 0.738), p
Subject: Sedation
endoscopic retrograde cholangiopancreatography
bispectral index
sedation scale
RANDOMIZED CONTROLLED-TRIAL
CONSCIOUS SEDATION
GASTROINTESTINAL ENDOSCOPY
DEEP SEDATION
INDEX
ERCP
GUIDELINES
MIDAZOLAM
PATIENT
ADJUNCT
3121 General medicine, internal medicine and other clinical medicine
3126 Surgery, anesthesiology, intensive care, radiology
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