The Prevalence of HSV, HHV-6, HPV and Mycoplasma genitalium in Chlamydia trachomatis positive and Chlamydia trachomatis Negative Urogenital Samples among Young Women in Finland

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dc.contributor University of Helsinki, HUSLAB en
dc.contributor University of Helsinki, Department of Virology en
dc.contributor University of Helsinki, HUS Gynecology and Obstetrics en
dc.contributor University of Helsinki, HUSLAB en
dc.contributor.author Korhonen, Suvi
dc.contributor.author Hokynar, Kati
dc.contributor.author Eriksson, Tiina
dc.contributor.author Natunen, Kari
dc.contributor.author Paavonen, Jorma
dc.contributor.author Lehtinen, Matti
dc.contributor.author Puolakkainen, Mirja
dc.date.accessioned 2020-02-25T10:48:01Z
dc.date.available 2020-02-25T10:48:01Z
dc.date.issued 2019-12-01
dc.identifier.citation Korhonen , S , Hokynar , K , Eriksson , T , Natunen , K , Paavonen , J , Lehtinen , M & Puolakkainen , M 2019 , ' The Prevalence of HSV, HHV-6, HPV and Mycoplasma genitalium in Chlamydia trachomatis positive and Chlamydia trachomatis Negative Urogenital Samples among Young Women in Finland ' , Pathogens , vol. 8 , no. 4 , 276 . https://doi.org/10.3390/pathogens8040276 en
dc.identifier.issn 2076-0817
dc.identifier.other PURE: 132657553
dc.identifier.other PURE UUID: c01d4261-4902-4ed3-94b5-67be5d5c0c2b
dc.identifier.other RIS: urn:01096B09AA21E3E462948E0EBAF930CF
dc.identifier.other WOS: 000506652300119
dc.identifier.other ORCID: /0000-0001-9424-8450/work/70943782
dc.identifier.other ORCID: /0000-0003-4775-606X/work/70945272
dc.identifier.other ORCID: /0000-0001-7413-6793/work/70946049
dc.identifier.uri http://hdl.handle.net/10138/312213
dc.description.abstract Chlamydia trachomatis, Mycoplasma genitalium, herpes simplex virus (HSV) and human papillomavirus (HPV) cause sexually transmitted infections. In addition, human herpesvirus 6 (HHV-6) may be a genital co-pathogen. The prevalence rates of HSV, HHV-6, HPV, M. genitalium, and the C. trachomatis ompA genotypes were investigated by PCR in urogenital samples of the C. trachomatis nucleic acid amplification test positive (n = 157) and age-, community- and time-matched negative (n = 157) women. The prevalence of HPV DNA was significantly higher among the C. trachomatis positives than the C. trachomatis negatives (66% vs. 25%, p <0.001). The prevalence of HSV (1.9% vs. 0%), HHV-6 (11% vs. 14%), and M. genitalium DNA (4.5% vs. 1.9%) was not significantly different between the C. trachomatis-positive and -negative women. Thirteen per cent of test-of-cure specimens tested positive for C. trachomatis. The prevalence of HSV, HHV-6, HPV, M. genitalium, and the C. trachomatis ompA genotypes did not significantly differ between those who cleared the C. trachomatis infection (n = 105) and those who did not (n = 16). The higher prevalence of HPV DNA among the C. trachomatis positives suggests greater sexual activity and increased risk for sexually transmitted pathogens. en
dc.format.extent 9
dc.language.iso eng
dc.relation.ispartof Pathogens
dc.rights en
dc.subject chlamydial co-infection en
dc.subject sexually transmitted infection en
dc.subject 3111 Biomedicine en
dc.subject 3123 Gynaecology and paediatrics en
dc.title The Prevalence of HSV, HHV-6, HPV and Mycoplasma genitalium in Chlamydia trachomatis positive and Chlamydia trachomatis Negative Urogenital Samples among Young Women in Finland en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.3390/pathogens8040276
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
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