Executive function subdomains are associated with post-stroke functional outcome and permanent institutionalization

Show full item record



Permalink

http://hdl.handle.net/10138/312564

Citation

Laakso , H M , Hietanen , M , Melkas , S , Sibolt , G , Curtze , S , Virta , M , Ylikoski , R , Pohjasvaara , T , Kaste , M , Erkinjuntti , T & Jokinen , H 2019 , ' Executive function subdomains are associated with post-stroke functional outcome and permanent institutionalization ' , European Journal of Neurology , vol. 26 , no. 3 , pp. 546-552 . https://doi.org/10.1111/ene.13854

Title: Executive function subdomains are associated with post-stroke functional outcome and permanent institutionalization
Author: Laakso, H. M.; Hietanen, M.; Melkas, S.; Sibolt, G.; Curtze, S.; Virta, M.; Ylikoski, R.; Pohjasvaara, T.; Kaste, M.; Erkinjuntti, T.; Jokinen, H.
Contributor: University of Helsinki, Department of Psychology and Logopedics
University of Helsinki, Clinicum
University of Helsinki, Department of Neurosciences
University of Helsinki, Clinicum
University of Helsinki, Neurologian yksikkö
University of Helsinki, Department of Psychology and Logopedics
University of Helsinki, Neurologian yksikkö
University of Helsinki, Clinicum
University of Helsinki, Clinicum
University of Helsinki, Department of Neurosciences
University of Helsinki, Clinicum
Date: 2019-03
Language: eng
Number of pages: 7
Belongs to series: European Journal of Neurology
ISSN: 1351-5101
URI: http://hdl.handle.net/10138/312564
Abstract: Background and purposeImpairment of executive functions (EFs) is a common cognitive symptom post-stroke and affects independence in daily activities. Previous studies have often relied on brief cognitive tests not fully considering the wide spectrum of EF subdomains. A detailed assessment of EFs was used to examine which of the subdomains and tests have the strongest predictive value on post-stroke functional outcome and institutionalization in long-term follow-up. MethodsA subsample of 62 patients from the Helsinki Stroke Aging Memory Study was evaluated with a battery of seven neuropsychological EF tests 3 months post-stroke and compared to 39 healthy control subjects. Functional impairment was evaluated with the modified Rankin Scale (mRS) and Instrumental Activities of Daily Living (IADL) scale at 3 months, and with the mRS at 15 months post-stroke. Institutionalization was reviewed from the national registers of permanent hospital admissions in up to 21-year follow-up. ResultsThe stroke group performed more poorly than the control group in multiple EF tests. Tests of inhibition, set shifting, initiation, strategy formation and processing speed were associated with the mRS and IADL scale in stroke patients. EF subdomain scores of inhibition, set shifting and processing speed were associated with functional outcome. In addition, inhibition was associated with the risk for earlier institutionalization. ConclusionsExecutive function was strongly associated with post-stroke functional impairment. In follow-up, poor inhibition was related to earlier permanent institutionalization. The results suggest the prognostic value of EF subdomains after stroke.
Subject: executive functions
functional impairment
functional outcome
institutionalization
neuropsychological assessment
stroke
COGNITIVE IMPAIRMENT
FRONTAL LOBES
STROKE
DYSFUNCTION
RELIABILITY
DEPRESSION
DEMENTIA
ADULTS
SPEED
3112 Neurosciences
3124 Neurology and psychiatry
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
Executive_function_subdomains.pdf 430.3Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record