Etiology of Childhood Otorrhea in Luanda, Angola, and a Review of Otitis Media in African Children

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dc.contributor University of Helsinki, HUS Children and Adolescents en
dc.contributor University of Helsinki, HUSLAB en
dc.contributor University of Helsinki, Department of Ophthalmology and Otorhinolaryngology en
dc.contributor University of Helsinki, Lastentautien yksikkö en
dc.contributor University of Helsinki, Children's Hospital en
dc.contributor.author Karppinen, Mariia
dc.contributor.author Bernardino, Luis
dc.contributor.author dos Anjos, Elizabete
dc.contributor.author Pätäri-Sampo, Anu
dc.contributor.author Pitkäranta, Anne
dc.contributor.author Peltola, Heikki
dc.contributor.author Pelkonen, Tuula
dc.date.accessioned 2020-03-05T03:20:45Z
dc.date.available 2021-09-19T02:45:43Z
dc.date.issued 2019-06
dc.identifier.citation Karppinen , M , Bernardino , L , dos Anjos , E , Pätäri-Sampo , A , Pitkäranta , A , Peltola , H & Pelkonen , T 2019 , ' Etiology of Childhood Otorrhea in Luanda, Angola, and a Review of Otitis Media in African Children ' , Pediatric Infectious Disease Journal , vol. 38 , no. 6 , pp. 577-581 . https://doi.org/10.1097/INF.0000000000002254 en
dc.identifier.issn 0891-3668
dc.identifier.other PURE: 125412887
dc.identifier.other PURE UUID: 9a4d5959-0fe2-4448-98f1-aa432aa8f545
dc.identifier.other WOS: 000468837600010
dc.identifier.other ORCID: /0000-0001-6714-3688/work/58955924
dc.identifier.uri http://hdl.handle.net/10138/312890
dc.description.abstract Background: In resource-poor settings, otorrhea causes a significant burden of disease in children. Etiologic studies and structured data on otorrhea and chronic otitis media among African children remain scarce. Methods: Here, we reviewed 678 bacteriologically analyzed otorrhea samples from Luanda Children's Hospital from children Results: Overall, 32 different bacteria were identified among 542 isolates from 654 children in Luanda. Gram-negative bacteria constituted the majority of all isolates (85%), whereby Pseudomonas spp. was the most common (n = 158; 29%), followed by Proteus spp. (n = 134; 25%). Among Staphylococcus aureus (n = 54; 10%), 69% of tested isolates were Methicillin-resistant S. aureus, and among Enterobacteriaceae, 14% were expanded-spectrum beta-lactamase isolates. Resistance to quinolones was rare. Furthermore, in a review of the literature, we found a high occurrence of otorrhea and chronic suppurative otitis media in children as well as possible gaps in existing knowledge. Conclusions: In Angola, Gram-negative rods emerged as common causative agents of otorrhea in children followed by S. aureus. The magnitude of chronic otorrhea in Africa represents a cause for public health concern. en
dc.format.extent 5
dc.language.iso eng
dc.relation.ispartof Pediatric Infectious Disease Journal
dc.rights en
dc.subject chronic suppurative otitis media en
dc.subject ear discharge en
dc.subject developing country en
dc.subject microbiology en
dc.subject child en
dc.subject BACTERIOLOGY en
dc.subject 3123 Gynaecology and paediatrics en
dc.subject 3125 Otorhinolaryngology, ophthalmology en
dc.title Etiology of Childhood Otorrhea in Luanda, Angola, and a Review of Otitis Media in African Children en
dc.type Review Article
dc.identifier.doi https://doi.org/10.1097/INF.0000000000002254
dc.type.uri info:eu-repo/semantics/other
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