Association between Meniere's disease and vestibular migraine

Show full item record



Permalink

http://hdl.handle.net/10138/312922

Citation

Pyykko , I , Manchaiah , V , Farkkila , M , Kentala , E & Zou , J 2019 , ' Association between Meniere's disease and vestibular migraine ' , Auris-nasus-larynx. , vol. 46 , no. 5 , pp. 724-733 . https://doi.org/10.1016/j.anl.2019.02.002

Title: Association between Meniere's disease and vestibular migraine
Author: Pyykko, Ilmari; Manchaiah, Vinaya; Farkkila, Markus; Kentala, Erna; Zou, Jing
Other contributor: University of Helsinki, HUS Head and Neck Center
University of Helsinki, HUS Head and Neck Center



Date: 2019-10
Language: eng
Number of pages: 10
Belongs to series: Auris-nasus-larynx.
ISSN: 0385-8146
DOI: https://doi.org/10.1016/j.anl.2019.02.002
URI: http://hdl.handle.net/10138/312922
Abstract: Objective: The aim of the present study was to evaluate complaints in people with Meniere's disease (MD) with and without migraine and headache to study the association between MD and Vestibular Migraine (VM). We believe this will help us understand if these two disorders represent a disease continuum in that they may share a common aetiology. Methods: The study used a retrospective design and included data of 911 patients with MD from the Finnish Meniere Federation database. The study participants had a mean age of 60.2 years, mean duration of disease of 12.6 years, and 78.7% of the participants were females. The questionnaire data comprised of both disease specific and impact related questions. The data were analyzed using the Mann-Whitney U test, the Kruskal Wallis H test, logistic regression analyses, and decision tree analysis. Results: Migraine and headache was reported by 190 subjects (20.9%) and 391 subjects (42.9%) respectively. We found that patients that could be classified as VM in the study (i.e., those with frequent vertigo spells associated with migraine) more often reported complaints of severe MD symptoms, had reduced health-related quality of life, suffered more from anxiety, had more neurological complaints, and experienced a reduced sense of coherence than the non-migraneous patients with MD. However, neither the decision tree analysis nor the logistic regression analysis could reliably discriminate VM from MD patients. Conclusion: Our study results confirm that MD is frequently associated with headache and migraine. In addition, results also indicate that migraine provokes the severity of MD. We suggest that MD and VM may share similar pathophysiological mechanisms. Hence, the future MD classification systems should include a category referred to as 'MD with migraine' that will include patients with VM. (C) 2019 Elsevier B.V. All rights reserved.
Subject: Meniere's disease
Vestibular migraine
Migraine
Headache
BENIGN RECURRENT VERTIGO
QUALITY-OF-LIFE
PEER SUPPORT
DIZZINESS
PREVALENCE
COHERENCE
SYMPTOMS
SENSE
POPULATION
DIAGNOSIS
3125 Otorhinolaryngology, ophthalmology
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
Association_bet ... nd_vestibular_migraine.pdf 625.4Kb PDF View/Open
Association_between.pdf 736.2Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record