Enzymatic assay for urine lactose in the assessment of recent intravenous abuse of buprenorphine

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http://hdl.handle.net/10138/312966

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Keltanen , T N , Heikman , P K , Muhonen , L H , Gunnar , T O & Ojanperä , I A 2019 , ' Enzymatic assay for urine lactose in the assessment of recent intravenous abuse of buprenorphine ' , Drug Testing and Analysis , vol. 11 , no. 9 , pp. 1412-1418 . https://doi.org/10.1002/dta.2654

Title: Enzymatic assay for urine lactose in the assessment of recent intravenous abuse of buprenorphine
Author: Keltanen, Terhi N.; Heikman, Pertti K.; Muhonen, Leea H.; Gunnar, Teemu O.; Ojanperä, Ilkka A.
Contributor: University of Helsinki, Department of Forensic Medicine
University of Helsinki, HUS Psychiatry
University of Helsinki, HUS Psychiatry
University of Helsinki, Department of Forensic Medicine
Date: 2019-09
Language: eng
Number of pages: 7
Belongs to series: Drug Testing and Analysis
ISSN: 1942-7603
URI: http://hdl.handle.net/10138/312966
Abstract: Urine samples were analyzed for lactose to investigate if elevated lactose concentrations indicate recent (<48 hours) intravenous abuse of substances containing lactose as an excipient. Elevated lactose levels were found in samples given by patients who had recently injected substances intravenously, verified by fresh injection marks. Urine lactose assay can support clinical and toxicological findings when assessing substance abuse.
Subject: buprenorphine
enzymatic assay
intravenous abuse
opioid dependence
urine lactose
MAINTENANCE TREATMENT MEDICATIONS
INTESTINAL PERMEABILITY
METHADONE
SUCROSE
DISACCHARIDES
DEPENDENCE
RAFFINOSE
DIVERSION
TABLETS
DRUGS
1182 Biochemistry, cell and molecular biology
317 Pharmacy
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