Pediatric malignancies in neurofibromatosis type 1 : A population-based cohort study

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http://hdl.handle.net/10138/312967

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Peltonen , S , Kallionpaa , R A , Rantanen , M , Uusitalo , E , Lähteenmäki , P M , Pöyhönen , M , Pitkäniemi , J & Peltonen , J 2019 , ' Pediatric malignancies in neurofibromatosis type 1 : A population-based cohort study ' , International Journal of Cancer , vol. 145 , no. 11 , pp. 2926-2932 . https://doi.org/10.1002/ijc.32187

Title: Pediatric malignancies in neurofibromatosis type 1 : A population-based cohort study
Author: Peltonen, Sirkku; Kallionpaa, Roope A.; Rantanen, Matti; Uusitalo, Elina; Lähteenmäki, Päivi M.; Pöyhönen, Minna; Pitkäniemi, Janne; Peltonen, Juha
Contributor: University of Helsinki, Department of Medical and Clinical Genetics
University of Helsinki, Staff Services
Date: 2019-12-01
Language: eng
Number of pages: 7
Belongs to series: International Journal of Cancer
ISSN: 0020-7136
URI: http://hdl.handle.net/10138/312967
Abstract: Neurofibromatosis type 1 (NF1) is a cancer predisposition syndrome with an incidence of 1:2,000. Patients with NF1 have an increased cancer risk and mortality, but there are no population-based cohort studies specifically investigating the risk of childhood malignancies. We used the Finnish NF1 cohort to analyze the incidence, risk and prognosis of malignancies in NF1 patients
Subject: astrocytoma
glioma
leukemia
malignant peripheral nerve sheath tumor
plexiform neurofibroma
NERVE SHEATH TUMORS
CHILDREN
CHILDHOOD
GLIOMAS
MORTALITY
DISEASE
MPNST
RISK
3122 Cancers
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