Pediatric malignancies in neurofibromatosis type 1 : A population-based cohort study
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Peltonen , S , Kallionpaa , R A , Rantanen , M , Uusitalo , E , Lähteenmäki , P M , Pöyhönen , M , Pitkäniemi , J & Peltonen , J 2019 , ' Pediatric malignancies in neurofibromatosis type 1 : A population-based cohort study ' , International Journal of Cancer , vol. 145 , no. 11 , pp. 2926-2932 . https://doi.org/10.1002/ijc.32187
| Title: | Pediatric malignancies in neurofibromatosis type 1 : A population-based cohort study |
| Author: | Peltonen, Sirkku; Kallionpaa, Roope A.; Rantanen, Matti; Uusitalo, Elina; Lähteenmäki, Päivi M.; Pöyhönen, Minna; Pitkäniemi, Janne; Peltonen, Juha |
| Contributor organization: | Department of Medical and Clinical Genetics HUSLAB Minna Pöyhönen / Principal Investigator University Management University of Helsinki Staff Services Department of Public Health Faculty of Medicine |
| Date: | 2019-12-01 |
| Language: | eng |
| Number of pages: | 7 |
| Belongs to series: | International Journal of Cancer |
| ISSN: | 0020-7136 |
| DOI: | https://doi.org/10.1002/ijc.32187 |
| URI: | http://hdl.handle.net/10138/312967 |
| Abstract: | Neurofibromatosis type 1 (NF1) is a cancer predisposition syndrome with an incidence of 1:2,000. Patients with NF1 have an increased cancer risk and mortality, but there are no population-based cohort studies specifically investigating the risk of childhood malignancies. We used the Finnish NF1 cohort to analyze the incidence, risk and prognosis of malignancies in NF1 patients |
| Subject: |
astrocytoma
glioma leukemia malignant peripheral nerve sheath tumor plexiform neurofibroma NERVE SHEATH TUMORS CHILDREN CHILDHOOD GLIOMAS MORTALITY DISEASE MPNST RISK 3122 Cancers |
| Peer reviewed: | Yes |
| Usage restriction: | openAccess |
| Self-archived version: | acceptedVersion |
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