Update on Canine Idiopathic Pulmonary Fibrosis in West Highland White Terriers

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Laurila , H P & Rajamäki , M M 2020 , ' Update on Canine Idiopathic Pulmonary Fibrosis in West Highland White Terriers ' , Veterinary Clinics of North America: Small Animal Practice , vol. 50 , no. 2 , pp. 431-446 . https://doi.org/10.1016/j.cvsm.2019.11.004

Title: Update on Canine Idiopathic Pulmonary Fibrosis in West Highland White Terriers
Author: Laurila, Henna P.; Rajamäki, Minna M.
Contributor: University of Helsinki, Equine and Small Animal Medicine
University of Helsinki, University Management
Date: 2020-03
Language: eng
Number of pages: 16
Belongs to series: Veterinary Clinics of North America: Small Animal Practice
ISSN: 0195-5616
URI: http://hdl.handle.net/10138/313238
Abstract: Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, progressive, interstitial lung disease (ILD) affecting older West Highland white terriers (WHWTs). According to one classification, CIPF is a familial fibrotic ILD in the group of idiopathic interstitial pneumonias. Etiology is unknown but likely arises from interplay between genetic and environmental factors. CIPF shares features with human idiopathic pulmonary fibrosis and human nonspecific interstitial pneumonia. This article describes clinical signs, findings in physical examination, arterial oxygenation, diagnostic imaging, bronchoscopy, bronchoalveolar lavage, histopathology, disease course, and outcome of WHWTs with CIPF; compares canine and human diseases; summarizes biomarker research; and gives an overview of potential treatment.
Subject: Dog
Interstitial lung disease
Idiopathic interstitial pneumonia
Arterial blood gas analysis
HRCT
Bronchoalveolar lavage
Biomarker
BRONCHOALVEOLAR LAVAGE FLUID
INTERSTITIAL LUNG-DISEASES
CHRONIC-BRONCHITIS
DOGS
RESOLUTION
SERUM
CLASSIFICATION
HYPERTENSION
CHEMOKINES
FEATURES
413 Veterinary science
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