Global Outcome Assessment Life-long after stroke in young adults initiative-the GOAL initiative : study protocol and rationale of a multicentre retrospective individual patient data meta-analysis

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Ekker , M S , Jacob , M A , van Dongen , M M E , Aarnio , K , Annamalai , A K , Arauz , A , Arnold , M , Barboza , M A , Bolognese , M , Brouns , R , Chuluun , B , Chuluunbaatar , E , Dagvajantsan , B , Debette , S , Don , A , Enzinger , C , Ekizoglu , E , Fandler-Hoefler , S , Fazekas , F , Fromm , A , Gattringer , T , Gulli , G , Hoffmann , M , Hora , T F , Jern , C , Jood , K , Kamouchi , M , Kim , Y S , Kitazono , T , Kittner , S J , Kleinig , T J , Klijn , C J M , Korv , J , Lee , T-H , Leys , D , Maaijwee , N A M , Martinez-Majander , N , Marto , J P , Mehndiratta , M M , Mifsud , V , Montanaro , V V , Owolabi , M O , Patel , V B , Phillips , M C , Piechowski-Iozwiak , B , Pikula , A , Luis Ruiz-Sandoval , J , Sarnowski , B , Schreuder , F H B M , Swartz , R H , Tan , K S , Tanne , D , Tatlisumak , T , Thijs , V , Tuladhar , A M , Viana-Baptista , M , Vibo , R , Wu , T Y , Yesilot , N , Waje-Andreassen , U , Pezzini , A , Putaala , J & de Leeuw , F-E 2019 , ' Global Outcome Assessment Life-long after stroke in young adults initiative-the GOAL initiative : study protocol and rationale of a multicentre retrospective individual patient data meta-analysis ' , BMJ Open , vol. 9 , no. 11 , 031144 . https://doi.org/10.1136/bmjopen-2019-031144

Title: Global Outcome Assessment Life-long after stroke in young adults initiative-the GOAL initiative : study protocol and rationale of a multicentre retrospective individual patient data meta-analysis
Author: Ekker, Merel S.; Jacob, Mina A.; van Dongen, Myrna M. E.; Aarnio, Karoliina; Annamalai, Arunkar K.; Arauz, Antonio; Arnold, Marcel; Barboza, Miguel A.; Bolognese, Manuel; Brouns, Raf; Chuluun, Batnairamdal; Chuluunbaatar, Enkhzaya; Dagvajantsan, Byambasuren; Debette, Stephanie; Don, Adi; Enzinger, Chris; Ekizoglu, Esme; Fandler-Hoefler, Simon; Fazekas, Franz; Fromm, Anette; Gattringer, Thomas; Gulli, Giosue; Hoffmann, Michael; Hora, Thiago F.; Jern, Christina; Jood, Katarina; Kamouchi, Masahiro; Kim, Young Seo; Kitazono, Takanari; Kittner, Steven J.; Kleinig, Timothy J.; Klijn, Catharina J. M.; Korv, Janika; Lee, Tsong-Hai; Leys, Didier; Maaijwee, Noortje A. M.; Martinez-Majander, Nicolas; Marto, Joao Pedro; Mehndiratta, Man M.; Mifsud, Victoria; Montanaro, Vinicius V.; Owolabi, Mayowa O.; Patel, Vinod B.; Phillips, Matthew C.; Piechowski-Iozwiak, Bartlomiej; Pikula, Aleksandra; Luis Ruiz-Sandoval, Jose; Sarnowski, Bettina; Schreuder, Floris H. B. M.; Swartz, Rick H.; Tan, K. S.; Tanne, David; Tatlisumak, T.; Thijs, Vincent; Tuladhar, Anil M.; Viana-Baptista, Miguel; Vibo, Riina; Wu, Teddy Y.; Yesilot, Nilufer; Waje-Andreassen, Ulrike; Pezzini, Alessandro; Putaala, Jukka; de Leeuw, Frank-Erik
Contributor: University of Helsinki, HUS Neurocenter
University of Helsinki, HUS Neurocenter
University of Helsinki, HUS Neurocenter
Date: 2019-11
Language: eng
Number of pages: 10
Belongs to series: BMJ Open
ISSN: 2044-6055
URI: http://hdl.handle.net/10138/313292
Abstract: Introduction Worldwide, 2 million patients aged 18-50 years suffer a stroke each year, and this number is increasing. Knowledge about global distribution of risk factors and aetiologies, and information about prognosis and optimal secondary prevention in young stroke patients are limited. This limits evidence-based treatment and hampers the provision of appropriate information regarding the causes of stroke, risk factors and prognosis of young stroke patients. Methods and analysis The Global Outcome Assessment Life-long after stroke in young adults (GOAL) initiative aims to perform a global individual patient data meta-analysis with existing data from young stroke cohorts worldwide. All patients aged 18-50 years with ischaemic stroke or intracerebral haemorrhage will be included. Outcomes will be the distribution of stroke aetiology and (vascular) risk factors, functional outcome after stroke, risk of recurrent vascular events and death and finally the use of secondary prevention. Subgroup analyses will be made based on age, gender, aetiology, ethnicity and climate of residence.
Subject: ISCHEMIC-STROKE
RISK-FACTORS
DISEASE
CLASSIFICATION
BURDEN
UPDATE
3112 Neurosciences
3124 Neurology and psychiatry
3121 General medicine, internal medicine and other clinical medicine
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