Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis : an EAACI position paper

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Hox , V , Lourijsen , E , Jordens , A , Aasbjerg , K , Agache , I , Alobid , I , Bachert , C , Boussery , K , Campo , P , Fokkens , W , Hellings , P , Hopkins , C , Klimek , L , Makelä , M , Moesges , R , Mullol , J , Pujols , L , Rondon , C , Rudenko , M , Toppila-Salmi , S , Scadding , G , Scheire , S , Tomazic , P-V , Van Zele , T , Wagemann , M , van Boven , J F M & Gevaert , P 2020 , ' Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis : an EAACI position paper ' , Clinical and Translational Allergy , vol. 10 , no. 1 , 1 . https://doi.org/10.1186/s13601-019-0303-6

Title: Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis : an EAACI position paper
Author: Hox, Valerie; Lourijsen, Evelijn; Jordens, Arnout; Aasbjerg, Kristian; Agache, Ioana; Alobid, Isam; Bachert, Claus; Boussery, Koen; Campo, Paloma; Fokkens, Wytske; Hellings, Peter; Hopkins, Claire; Klimek, Ludger; Makelä, Mika; Moesges, Ralph; Mullol, Joaquim; Pujols, Laura; Rondon, Carmen; Rudenko, Michael; Toppila-Salmi, Sanna; Scadding, Glenis; Scheire, Sophie; Tomazic, Peter-Valentin; Van Zele, Thibaut; Wagemann, Martin; van Boven, Job F. M.; Gevaert, Philippe
Contributor: University of Helsinki, HUS Inflammation Center
University of Helsinki, HUS Inflammation Center
Date: 2020-01-03
Language: eng
Number of pages: 27
Belongs to series: Clinical and Translational Allergy
ISSN: 2045-7022
URI: http://hdl.handle.net/10138/313348
Abstract: Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that-potentially severe-side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.
Subject: Glucocorticosteroids
Rhinitis
Rhinosinusitis
GLUCOCORTICOID-RECEPTOR-ALPHA
ENDOSCOPIC SINUS SURGERY
SEASONAL ALLERGIC RHINITIS
SEVERE NASAL POLYPOSIS
BONE-MINERAL DENSITY
CORTICOSTEROID-THERAPY
RHEUMATOID-ARTHRITIS
ORAL STEROIDS
DOUBLE-BLIND
WEGENERS-GRANULOMATOSIS
3121 General medicine, internal medicine and other clinical medicine
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