Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019

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http://hdl.handle.net/10138/313363

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Weinbaum , B , Williams , A , Hadad , R , Vinluan , B , Puolakkainen , M , Unemo , M & Getman , D 2020 , ' Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019 ' , Eurosurveillance , vol. 25 , no. 5 , 2000038 , pp. 16-22 . https://doi.org/10.2807/1560-7917.ES.2020.25.5.2000038

Titel: Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019
Författare: Weinbaum, Barbara; Williams, Analee; Hadad, Ronza; Vinluan, Bryan; Puolakkainen, Mirja; Unemo, Magnus; Getman, Damon
Medarbetare: University of Helsinki, HUSLAB
Datum: 2020-02-06
Språk: eng
Sidantal: 7
Tillhör serie: Eurosurveillance
ISSN: 1560-7917
Permanenta länken (URI): http://hdl.handle.net/10138/313363
Abstrakt: The Finnish new variant of Chlamydia trachomatis (FI-nvCT) is escaping diagnostics in Finland, Norway and Sweden. We have developed and validated an Aptima-format nucleic acid amplification test (NAAT) designed specifically to detect the FI-nvCT. This NAAT has high sensitivity (100%) and specificity (100%) for the FI-nvCT strain, enabling further investigation of the geographic distribution, prevalence and transmission of this diagnostic-escape mutant in screening populations in Europe.
Subject: 3121 Internal medicine
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