OBEDIS Core Variables Project : European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions

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dc.contributor.author Alligier, Maud
dc.contributor.author Barres, Romain
dc.contributor.author Blaak, Ellen E.
dc.contributor.author Boirie, Yves
dc.contributor.author Bouwman, Jildau
dc.contributor.author Brunault, Paul
dc.contributor.author Campbell, Kristina
dc.contributor.author Clement, Karine
dc.contributor.author Farooqi, I. Sadaf
dc.contributor.author Farpour-Lambert, Nathalie J.
dc.contributor.author Fruhbeck, Gema
dc.contributor.author Goossens, Gijs H.
dc.contributor.author Hager, Jorg
dc.contributor.author Halford, Jason C. G.
dc.contributor.author Hauner, Hans
dc.contributor.author Jacobi, David
dc.contributor.author Julia, Chantal
dc.contributor.author Langin, Dominique
dc.contributor.author Natali, Andrea
dc.contributor.author Neovius, Martin
dc.contributor.author Oppert, Jean Michel
dc.contributor.author Pagotto, Uberto
dc.contributor.author Palmeira, Antonio L.
dc.contributor.author Roche, Helen
dc.contributor.author Ryden, Mikael
dc.contributor.author Scheen, Andre J.
dc.contributor.author Simon, Chantal
dc.contributor.author Sorensen, Thorkild I. A.
dc.contributor.author Tappy, Luc
dc.contributor.author Yki-Järvinen, Hannele
dc.contributor.author Ziegler, Olivier
dc.contributor.author Laville, Martine
dc.date.accessioned 2020-03-31T06:03:01Z
dc.date.available 2020-03-31T06:03:01Z
dc.date.issued 2020-02
dc.identifier.citation Alligier , M , Barres , R , Blaak , E E , Boirie , Y , Bouwman , J , Brunault , P , Campbell , K , Clement , K , Farooqi , I S , Farpour-Lambert , N J , Fruhbeck , G , Goossens , G H , Hager , J , Halford , J C G , Hauner , H , Jacobi , D , Julia , C , Langin , D , Natali , A , Neovius , M , Oppert , J M , Pagotto , U , Palmeira , A L , Roche , H , Ryden , M , Scheen , A J , Simon , C , Sorensen , T I A , Tappy , L , Yki-Järvinen , H , Ziegler , O & Laville , M 2020 , ' OBEDIS Core Variables Project : European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions ' , Obesity facts , vol. 13 , no. 1 , pp. 1-28 . https://doi.org/10.1159/000505342
dc.identifier.other PURE: 134578662
dc.identifier.other PURE UUID: fae1147e-949f-419f-af83-d745d7c20db9
dc.identifier.other WOS: 000518585900001
dc.identifier.uri http://hdl.handle.net/10138/313769
dc.description.abstract Heterogeneity of interindividual and intraindividual responses to interventions is often observed in randomized, controlled trials for obesity. To address the global epidemic of obesity and move toward more personalized treatment regimens, the global research community must come together to identify factors that may drive these heterogeneous responses to interventions. This project, called OBEDIS (OBEsity Diverse Interventions Sharing - focusing on dietary and other interventions), provides a set of European guidelines for a minimal set of variables to include in future clinical trials on obesity, regardless of the specific endpoints. Broad adoption of these guidelines will enable researchers to harmonize and merge data from multiple intervention studies, allowing stratification of patients according to precise phenotyping criteria which are measured using standardized methods. In this way, studies across Europe may be pooled for better prediction of individuals' responses to an intervention for obesity - ultimately leading to better patient care and improved obesity outcomes. en
dc.format.extent 28
dc.language.iso eng
dc.relation.ispartof Obesity facts
dc.rights cc_by_nc_nd
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Obesity
dc.subject Interventions
dc.subject Variables
dc.subject Precision medicine
dc.subject Stratification
dc.subject CORONARY-HEART-DISEASE
dc.subject QUALITY-OF-LIFE
dc.subject OBSTRUCTIVE SLEEP-APNEA
dc.subject C-REACTIVE PROTEIN
dc.subject BODY-MASS INDEX
dc.subject GASTRIC BYPASS-SURGERY
dc.subject WEIGHT-LOSS
dc.subject PHYSICAL-ACTIVITY
dc.subject METABOLIC SYNDROME
dc.subject CARDIOVASCULAR-DISEASE
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title OBEDIS Core Variables Project : European Expert Guidelines on a Minimal Core Set of Variables to Include in Randomized, Controlled Clinical Trials of Obesity Interventions en
dc.type Article
dc.contributor.organization Department of Medicine
dc.contributor.organization HUS Internal Medicine and Rehabilitation
dc.contributor.organization University of Helsinki
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1159/000505342
dc.relation.issn 1662-4025
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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