Modular chromosome rearrangements reveal parallel and nonparallel adaptation in a marine fish

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dc.contributor.author Kess, Tony
dc.contributor.author Bentzen, Paul
dc.contributor.author Lehnert, Sarah J.
dc.contributor.author Sylvester, Emma V.A.
dc.contributor.author Lien, Sigbjørn
dc.contributor.author Kent, Matthew P.
dc.contributor.author Sinclair-Waters, Marion
dc.contributor.author Morris, Corey J.
dc.contributor.author Wringe, Brendan
dc.contributor.author Fairweather, Robert
dc.contributor.author Bradbury, Ian R.
dc.date.accessioned 2020-04-01T14:47:02Z
dc.date.available 2020-04-01T14:47:02Z
dc.date.issued 2020-01-11
dc.identifier.citation Kess , T , Bentzen , P , Lehnert , S J , Sylvester , E V A , Lien , S , Kent , M P , Sinclair-Waters , M , Morris , C J , Wringe , B , Fairweather , R & Bradbury , I R 2020 , ' Modular chromosome rearrangements reveal parallel and nonparallel adaptation in a marine fish ' , Ecology and Evolution , vol. 10 , no. 2 , pp. 638–653 . https://doi.org/10.1002/ece3.5828
dc.identifier.other PURE: 130373750
dc.identifier.other PURE UUID: e2796207-0235-47e9-816a-46dc18d9c5ac
dc.identifier.other WOS: 000506551200001
dc.identifier.other ORCID: /0000-0001-7371-4547/work/71513929
dc.identifier.uri http://hdl.handle.net/10138/313848
dc.description.abstract Genomic architecture and standing variation can play a key role in ecological adaptation and contribute to the predictability of evolution. In Atlantic cod (Gadus morhua), four large chromosomal rearrangements have been associated with ecological gradients and migratory behavior in regional analyses. However, the degree of parallelism, the extent of independent inheritance, and functional distinctiveness of these rearrangements remain poorly understood. Here, we use a 12K single nucleotide polymorphism (SNP) array to demonstrate extensive individual variation in rearrangement genotype within populations across the species range, suggesting that local adaptation to fine-scale ecological variation is enabled by rearrangements with independent inheritance. Our results demonstrate significant association of rearrangements with migration phenotype and environmental gradients across the species range. Individual rearrangements exhibit functional modularity, but also contain loci showing multiple environmental associations. Clustering in genetic distance trees and reduced differentiation within rearrangements across the species range are consistent with shared variation as a source of contemporary adaptive diversity in Atlantic cod. Conversely, we also find that haplotypes in the LG12 and LG1 rearranged region have diverged across the Atlantic, despite consistent environmental associations. Exchange of these structurally variable genomic regions, as well as local selective pressures, has likely facilitated individual diversity within Atlantic cod stocks. Our results highlight the importance of genomic architecture and standing variation in enabling fine-scale adaptation in marine species. en
dc.format.extent 16
dc.language.iso eng
dc.relation.ispartof Ecology and Evolution
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject 1181 Ecology, evolutionary biology
dc.subject Atlantic cod
dc.subject environmental association
dc.subject genomic architecture
dc.subject marine
dc.subject migration
dc.subject parallel evolution
dc.subject ATLANTIC COD ECOTYPES
dc.subject LOCAL ADAPTATION
dc.subject GENOMIC ARCHITECTURE
dc.subject ADAPTIVE EVOLUTION
dc.subject POPULATION-GENETICS
dc.subject R PACKAGE
dc.subject INVERSIONS
dc.subject DIVERGENCE
dc.subject SPECIATION
dc.subject SELECTION
dc.title Modular chromosome rearrangements reveal parallel and nonparallel adaptation in a marine fish en
dc.type Article
dc.contributor.organization Evolution, Conservation, and Genomics
dc.contributor.organization Organismal and Evolutionary Biology Research Programme
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1002/ece3.5828
dc.relation.issn 2045-7758
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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