Yard vegetation is associated with gut microbiota composition

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http://hdl.handle.net/10138/314034

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Parajuli , A , Hui , N , Puhakka , R , Oikarinen , S , Grönroos , M , Selonen , V A O , Siter , N , Kramna , L , Roslund , M , Vari , H , Nurminen , N , Honkanen , H , Hintikka , J , Sarkkinen , H , Romantschuk , M L , Kauppi , M , Valve , R , Cinek , O , Laitinen , O H , Rajaniemi , J , Hyöty , H , Sinkkonen , A & The ADELE Research Group 2020 , ' Yard vegetation is associated with gut microbiota composition ' , The Science of the Total Environment , vol. 713 , 136707 . https://doi.org/10.1016/j.scitotenv.2020.136707

Title: Yard vegetation is associated with gut microbiota composition
Author: Parajuli, Anirudra; Hui, Nan; Puhakka, Riikka; Oikarinen, Sami; Grönroos, Mira; Selonen, Ville A. O.; Siter, Nathan; Kramna, Lenka; Roslund, Marja; Vari, Heli; Nurminen, Noora; Honkanen, Hanna; Hintikka, Jukka; Sarkkinen, Hannu; Romantschuk, Martin L.; Kauppi, Markku; Valve, Raisa; Cinek, Ondrej; Laitinen, Olli H.; Rajaniemi, Juho; Hyöty, Heikki; Sinkkonen, Aki; The ADELE Research Group
Other contributor: University of Helsinki, Ecosystems and Environment Research Programme
University of Helsinki, Ecosystems and Environment Research Programme
University of Helsinki, Ecosystems and Environment Research Programme
University of Helsinki, Nature-Based Solutions
University of Helsinki, Helsinki Institute of Sustainability Science (HELSUS)
University of Helsinki, Ecosystems and Environment Research Programme
University of Helsinki, Nature-Based Solutions
University of Helsinki, HYKS erva
University of Helsinki, HYKS erva
University of Helsinki, Ecosystems and Environment Research Programme
University of Helsinki, HYKS erva
University of Helsinki, Nutrition Science
University of Helsinki, Ecosystems and Environment Research Programme







Date: 2020-04-15
Language: eng
Number of pages: 8
Belongs to series: The Science of the Total Environment
ISSN: 0048-9697
DOI: https://doi.org/10.1016/j.scitotenv.2020.136707
URI: http://hdl.handle.net/10138/314034
Abstract: Gut microbes play an essential role in the development and functioning of the human immune system. A disturbed gut microbiota composition is often associated with a number of health disorders including immune-mediated diseases. Differences in host characteristics such as ethnicity, living habit and diet have been used to explain differences in the gut microbiota composition in inter-continental comparison studies. As our previous studies imply that daily skin contact with organic gardening materials modify gut microflora, here we investigated the association between living environment and gut microbiota in a homogenous western population along an urban-rural gradient. We obtained stool samples from 48 native elderly Finns in province Hame in August and November 2015 and identified the bacterial phylotypes using 16S rRNA Illumina MiSeq sequencing. We assumed that yard vegetation and land cover classes surrounding homes explain the stool bacterial community in generalized linear mixed models. Diverse yard vegetation was associated with a reduced abundance of Clostridium sensu stricto and an increased abundance of Faecalibacterium and Prevotellaceae. The abundance of Bacteroides was positively and strongly associated with the built environment. Exclusion of animal owners did not alter the main associations. These results suggest that diverse vegetation around homes is associated with health-related changes in gut microbiota composition. Manipulation of the garden diversity, possibly jointly with urban planning, is a promising candidate for future intervention studies that aim to maintain gut homeostasis. (C) 2020 The Authors. Published by Elsevier B.V.
Subject: 1172 Environmental sciences
Gut microbiota
Elderly gut microbiota
Living environment
Garden diversity
Built area coverage
HEALTH
SENSITIZATION
ALLERGY
BACTEROIDES
PREVALENCE
PREVOTELLA
CHILDREN
DISEASE
AREAS
RISK
3142 Public health care science, environmental and occupational health
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