Time course of signaling profiles of blood leukocytes in acute pancreatitis and sepsis
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Turunen , A , Kuuliala , A , Penttilä , A , Kaukonen , K-M , Mustonen , H , Pettilä , V , Puolakkainen , P , Kylänpää , L & Kuuliala , K 2020 , ' Time course of signaling profiles of blood leukocytes in acute pancreatitis and sepsis ' , Scandinavian Journal of Clinical & Laboratory Investigation , vol. 80 , no. 2 , pp. 114-123 . https://doi.org/10.1080/00365513.2019.1700548
| Title: | Time course of signaling profiles of blood leukocytes in acute pancreatitis and sepsis |
| Author: | Turunen, Antti; Kuuliala, Antti; Penttilä, Anne; Kaukonen, Kirsi-Maija; Mustonen, Harri; Pettilä, Ville; Puolakkainen, Pauli; Kylänpää, Leena; Kuuliala, Krista |
| Contributor organization: | HUS Abdominal Center University of Helsinki II kirurgian klinikka Medicum Department of Bacteriology and Immunology HUSLAB Clinicum Department of Surgery HUS Perioperative, Intensive Care and Pain Medicine Department of Diagnostics and Therapeutics Anestesiologian yksikkö University Management Pauli Puolakkainen / Principal Investigator Teachers' Academy |
| Date: | 2020-02-17 |
| Language: | eng |
| Number of pages: | 10 |
| Belongs to series: | Scandinavian Journal of Clinical & Laboratory Investigation |
| ISSN: | 0036-5513 |
| DOI: | https://doi.org/10.1080/00365513.2019.1700548 |
| URI: | http://hdl.handle.net/10138/314492 |
| Abstract: | Activation of intracellular signaling pathways in circulating leukocytes represents an early step in systemic immune-inflammatory response occurring e.g. in acute pancreatitis (AP) and sepsis. Previously, we found aberrations in the phosphorylation of leukocyte signaling proteins in patients with sepsis or AP (measured |
| Subject: |
Pancreatitis
sepsis leukocytes flow cytometry signal transduction NF-KAPPA-B ORGAN FAILURE INFLAMMATION EXPRESSION SEVERITY MONOCYTE IMMUNOSUPPRESSION DEFINITIONS MACROPHAGES NEUTROPHILS 3111 Biomedicine 3121 General medicine, internal medicine and other clinical medicine 3126 Surgery, anesthesiology, intensive care, radiology |
| Peer reviewed: | Yes |
| Rights: | unspecified |
| Usage restriction: | openAccess |
| Self-archived version: | acceptedVersion |
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Articles from TUHAT CRIS [50259]