Complete Atrioventricular Septal Defect : Evolution of Results in a Single Center During 50 Years

Show full item record



Permalink

http://hdl.handle.net/10138/315094

Citation

Airaksinen , R , Mattila , I , Jokinen , E , Salminen , J , Puntila , J , Lehtinen , M L , Ojala , T , Rautiainen , P , Rahkonen , O , Suominen , P & Pätilä , T 2019 , ' Complete Atrioventricular Septal Defect : Evolution of Results in a Single Center During 50 Years ' , Annals of Thoracic Surgery , vol. 107 , no. 6 , pp. 1824-1830 . https://doi.org/10.1016/j.athoracsur.2019.01.020

Title: Complete Atrioventricular Septal Defect : Evolution of Results in a Single Center During 50 Years
Author: Airaksinen, Riku; Mattila, Ilkka; Jokinen, Eero; Salminen, Jukka; Puntila, Juha; Lehtinen, Miia L.; Ojala, Tilna; Rautiainen, Paula; Rahkonen, Otto; Suominen, Pertti; Pätilä, Tommi
Contributor: University of Helsinki, Clinicum
University of Helsinki, Children's Hospital
University of Helsinki, Lastentautien yksikkö
University of Helsinki, Children's Hospital
University of Helsinki, Children's Hospital
University of Helsinki, HUS Children and Adolescents
University of Helsinki, Children's Hospital
University of Helsinki, Children's Hospital
University of Helsinki, HUS Children and Adolescents
University of Helsinki, HUS Children and Adolescents
Date: 2019-06
Number of pages: 7
Belongs to series: Annals of Thoracic Surgery
ISSN: 0003-4975
URI: http://hdl.handle.net/10138/315094
Abstract: Background. Operative mortality after complete atrioventricular septal defect (cAVSD) repair has improved vastly. Less improvement has been demonstrated regarding late mortality and reoperation rates, however. There is evident lack of comprehensive population-based studies analyzing the history and progress of the ever-changing operative results. Methods. This is a 5-million population-based retrospective study of consecutive 388 cAVSD patients operated in Finland between 1962 and 2014. Data were collected using Children's Cardiac Surgical Registry of Children's Hospital at the Helsinki University Hospital, Finland. Mortality data and reoperation rates were analyzed on a decade-by-decade basis. Results. During the early era, overall mortality was 17.4%, operative mortality constituting 10.9%. The operative results have improved significantly over the decades, and eventually, the last decade showed no mortality. A total of 23 late deaths occurred; of these, 20 were directly heart-related. Half of the late mortality occurred during the first postoperative year. The only significant risk factor for overall mortality was an earlier decade of operation (p <0.001). Reoperation rates have not decreased but slightly increased over decades (p = 0.621), and reoperations have been performed mainly during the first year after the primary operation. Actuarial freedom from left side atrioventricular valve reoperation at 15 years was 90.9%. Conclusions. There has been an outstanding improvement in surgical results through the years even though the general operative approach has remained the same. Rates of reoperation have not been declining, but the reoperations are dated to early childhood years. The improvement in results has been ongoing. (C) 2019 by The Society of Thoracic Surgeons
Subject: SURGICAL REPAIR
DOWN-SYNDROME
OUTCOMES
SOCIETY
3126 Surgery, anesthesiology, intensive care, radiology
Rights:
Full text embargoed until: 2020-05-22


Files in this item

Files Size Format View

Embargo on files ends: 2020-05-22

This item appears in the following Collection(s)

Show full item record