Meal Regularity Plays a Role in Shaping the Saliva Microbiota

Show full item record



Permalink

http://hdl.handle.net/10138/315825

Citation

Viljakainen , J , Raju , S C , Viljakainen , H , Figueiredo , R A D O , Roos , E , Weiderpass , E & Rounge , T B 2020 , ' Meal Regularity Plays a Role in Shaping the Saliva Microbiota ' , Frontiers in Microbiology , vol. 11 , 757 . https://doi.org/10.3389/fmicb.2020.00757

Title: Meal Regularity Plays a Role in Shaping the Saliva Microbiota
Author: Viljakainen, Jannina; Raju, Sajan C.; Viljakainen, Heli; Figueiredo, Rejane Augusta de Oliveira; Roos, Eva; Weiderpass, Elisabete; Rounge, Trine B.
Contributor: University of Helsinki, Faculty of Medicine
University of Helsinki, General Microbiology
University of Helsinki, HUS Children and Adolescents
University of Helsinki, Medicum
University of Helsinki, Clinicum
University of Helsinki, World Health Organization
Date: 2020-04-24
Language: eng
Number of pages: 11
Belongs to series: Frontiers in Microbiology
ISSN: 1664-302X
URI: http://hdl.handle.net/10138/315825
Abstract: Background Diet may influence health directly or indirectly via the human microbiota, emphasizing the need to unravel these complex relationships for future health benefits. Associations between eating habits and gut microbiota have been shown, but less is known about the association between eating habits and saliva microbiota. Objective The aim of this study was to investigate if eating habits and meal patterns are associated with the saliva microbiota. Methods In total, 842 adolescents, aged 11-14 years, from the Finnish Health in Teens (Fin-HIT) study cohort were included in this study. Eating habits and breakfast and dinner patterns were derived from a web-based questionnaire answered in school. Three major eating habit groups were identified: fruit and vegetable avoiders (FV avoiders), healthy and unhealthy. Microbiota profiles were produced from 16S rRNA gene (V3-V4) sequencing of DNA from the saliva samples. Statistical models were adjusted for gender, age, parental language, body mass index (BMI) categories, and sequencing depth. Results Regular breakfast eaters had a higher alpha diversity (Shannon index with mean (standard error of means) 2.27 (0.03) vs. 2.22 (0.03), p = 0.06, inverse Simpson's index with 6.27 (0.17) vs. 5.80 (0.02), p = 0.01), and slight differences in bacterial composition (PERMANOVA: p = 0.001) compared with irregular breakfast eaters. A similar trend in alpha diversity was observed between regular and irregular dinner eaters (Shannon index with 2.27 (0.03) vs. 2.22 (0.03), p = 0.054, inverse Simpson's index with 6.23 (0.17) vs. 6.04 (0.22), p = 0.28), while no difference was found in composition (PERMANOVA: p = 0.08). No differences were identified between eating habit groups and saliva microbiota diversity (Shannon index p = 0.77, inverse Simpson's index p = 0.94) or composition (PERMANOVA: p = 0.13). FV avoiders, irregular breakfast eaters and irregular dinner eaters had high abundances of Prevotella. Conclusion Regularity of eating, especially breakfast eating, was associated with more diverse saliva microbiota and different composition compared with irregular eaters. However, the dissimilarities in composition were small between regular and irregular breakfast eaters. Our results suggest that Prevotella abundances in saliva were common in FV avoiders and meal skippers. However, the clinical implications of these findings need to be evaluated in future studies.
Subject: 11832 Microbiology and virology
3143 Nutrition
eating habits
saliva
human microbiota
breakfast
dinner
adolescent
FOOD-INTAKE
ADOLESCENTS
WEIGHT
OVERWEIGHT
BREAKFAST
CHILDREN
EUROPE
IMPACT
STYLE
DIET
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
fmicb_11_00757.pdf 1.329Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record