Gut microbes and Parkinson’s disease

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http://urn.fi/URN:NBN:fi:hulib-202006052573
Title: Gut microbes and Parkinson’s disease
Author: Huynh, Anh Vy
Contributor: University of Helsinki, Faculty of Agriculture and Forestry
Publisher: Helsingin yliopisto
Date: 2020
Language: eng
URI: http://urn.fi/URN:NBN:fi:hulib-202006052573
http://hdl.handle.net/10138/315891
Thesis level: master's thesis
Degree program: Mikrobiologian ja mikrobibiotekniikan maisteriohjelma
Master's Programme in Microbiology and Microbial Biotechnology
Magisterprogrammet i mikrobiologi och mikrobibioteknik
Specialisation: ei opintosuuntaa
no specialization
ingen studieinriktning
Abstract: Parkinson’s disease is a common neurodegenerative disorder that affects the movement. Although the disease has been known for a long time and intensive studies on this subject have been carried out, the cause of the disease is still unidentified. Interestingly, certain metallic molecules have been found in the neurodegenerative tissues. The metabolism of certain bacterial species has been found to be responsible for the accumulation of these molecules. In this study, we investigated the association between five specific species of gut bacteria, as well as their putative role in the accumulation of the metallic molecules and Parkinson’s disease. The methods comprised of molecular assays for detection and quantification of the bacteria, respectively, from feces samples derived from healthy individuals (n=20) and patients with the disease (n=20). The outcome of molecular assays was verified by traditional microbiological methods. The results suggested that more studies should be done to verify any role of these bacteria in Parkinson ́s disease.
Subject: Parkinson’s disease
intestinal bacteria
Full text embargoed until: 2023-06-02


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