Twin studies on the association of physical activity with cognitive and cerebral outcomes

Show full item record



Permalink

http://hdl.handle.net/10138/316984

Citation

Iso-Markku , P , Waller , K , Hautasaari , P , Kaprio , J , Kujala , U M & Tarkka , I M 2020 , ' Twin studies on the association of physical activity with cognitive and cerebral outcomes ' , Neuroscience & Biobehavioral Reviews , vol. 114 , pp. 1-11 . https://doi.org/10.1016/j.neubiorev.2020.04.015

Title: Twin studies on the association of physical activity with cognitive and cerebral outcomes
Author: Iso-Markku, Paula; Waller, Katja; Hautasaari, Pekka; Kaprio, Jaakko; Kujala, Urho M.; Tarkka, Ina M.
Contributor: University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Institute for Molecular Medicine Finland
Date: 2020-07
Language: eng
Number of pages: 11
Belongs to series: Neuroscience & Biobehavioral Reviews
ISSN: 0149-7634
URI: http://hdl.handle.net/10138/316984
Abstract: Regular physical activity (PA) offers positive effects on the human body. However, the effects of PA on cognition and in the brain are less clear. In this paper, we narratively review the relationship of PA with cognition and dementia, first from general perspective and then through genetically informed studies on the topic. Then we move on to imaging studies on exercise and brain anatomy first by presenting an overall picture of the topic and then discussing brain imaging studies addressing PA and brain structure in twins in more detailed way. Regarding PA and cognition or dementia, genetically informed studies are uncommon, even though the relationship between PA and cognitive ageing has been extensively studied. It is challenging to find twin pairs discordant for PA and dementia. Concerning brain imaging studies, among PA discordant young adult twin pairs, the more active co-twins showed larger gray matter volumes in striatal, prefrontal, and hippocampal regions and in electrophysiological studies automatic deviance-detection processes differed in brain regions involved with sensorimotor, visual and memory functions.
Subject: 3112 Neurosciences
3124 Neurology and psychiatry
Cognition
Age-related brain changes
Dementia
Leisure-time physical activity
Structural MRI
Electroencephalography
Mismatch negativity
Somatosensory system
RISK-FACTORS
OLDER-ADULTS
ALZHEIMERS-DISEASE
AMYLOID LOAD
MISMATCH NEGATIVITY
MONOZYGOTIC TWINS
BRAIN MORPHOLOGY
AEROBIC EXERCISE
HIPPOCAMPAL NEUROGENESIS
NEUROCOGNITIVE PERFORMANCE
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
1_s2.0_S0149763419306402_main.pdf 373.9Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record