Weight gain may affect mandibular advancement device therapy in patients with obstructive sleep apnea : a retrospective study

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http://hdl.handle.net/10138/317093

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Vuorjoki-Ranta , T-R , Aarab , G , Lobbezoo , F , Tuomilehto , H & Ahlberg , J 2019 , ' Weight gain may affect mandibular advancement device therapy in patients with obstructive sleep apnea : a retrospective study ' , Sleep and Breathing , vol. 23 , no. 2 , pp. 531-534 . https://doi.org/10.1007/s11325-018-1728-1

Title: Weight gain may affect mandibular advancement device therapy in patients with obstructive sleep apnea : a retrospective study
Author: Vuorjoki-Ranta, Tiina-Riitta; Aarab, Ghizlane; Lobbezoo, Frank; Tuomilehto, Henri; Ahlberg, Jari
Contributor: University of Helsinki, Clinicum
Date: 2019-06
Language: eng
Number of pages: 4
Belongs to series: Sleep and Breathing
ISSN: 1520-9512
URI: http://hdl.handle.net/10138/317093
Abstract: Purpose The aim was to analyze whether or not weight gain influences the treatment outcome of patients with obstructive sleep apnea (OSA) treated with mandibular advancement devices (MAD). Methods As a part of a follow-up study among OSA patients treated with MAD in primary oral health care, a group of 28 patients reporting worsening of daytime or nighttime symptoms of OSA was given closer examination. Altogether, 21 subjects had a complete set of recordings and were enrolled into the study. Results Only three subjects had lost weight during the study period. The mean weight gain of 3.6kg7.1kg was significant (p=0.035). According to linear regression, weight gain was independently significantly associated with lower mean peripheral oxygen saturation 92.4 (SD 1.8 (% per hour) (p=0.019)) and lowest oxygen saturation 80.1 (SD 7.2 (%) (p=0.024)) scores. Conclusions Weight gain is detrimentally associated with MAD treatment in patients with OSA. These findings suggest that regular follow-up by an experienced dentist is advisable to assess for possible worsening of OSA. Patient support to encourage weight control may be an important adjunct to MAD treatment for OSA.
Subject: Obstructive sleep apnea
Mandibular advancement device
Overweight
Primary health care
ORAL APPLIANCE THERAPY
CONTROLLED-TRIAL
GUIDELINE
PRESSURE
MODERATE
EVENTS
CPAP
LIFE
CARE
3112 Neurosciences
3124 Neurology and psychiatry
3121 General medicine, internal medicine and other clinical medicine
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