Smoking during pregnancy reduces vitamin D levels in a Finnish birth register cohort

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Lokki , A I , Heikkinen-Eloranta , J , Öhman , H , Heinonen , S , Surcel , H-M & Nielsen , H S 2020 , ' Smoking during pregnancy reduces vitamin D levels in a Finnish birth register cohort ' , Public Health Nutrition , vol. 23 , no. 7 , 1368980018003932 , pp. 1273-1277 . https://doi.org/10.1017/S1368980018003932

Title: Smoking during pregnancy reduces vitamin D levels in a Finnish birth register cohort
Author: Lokki, A. Inkeri; Heikkinen-Eloranta, Jenni; Öhman, Hanna; Heinonen, Seppo; Surcel, Heljä-Marja; Nielsen, Henriette Svarre
Contributor: University of Helsinki, Immunobiology Research Program
University of Helsinki, Pregnancy and Genes
University of Helsinki, HUS Gynecology and Obstetrics
Date: 2020-05
Number of pages: 5
Belongs to series: Public Health Nutrition
ISSN: 1368-9800
URI: http://hdl.handle.net/10138/317499
Abstract: Objective Maternal vitamin D level in pregnancy may have implications for both the mother and fetus. Deficiency of vitamin D has been linked to several pregnancy complications and fetal skeletal health. Smoking has been associated with reduced serum level of the vitamin D metabolite, 25-hydroxyvitamin D (25(OH)D). Design A nested case-control study within the Finnish Maternity Cohort, a population-based cohort which includes first-trimester sera from 98 % of pregnancies in Finland since 1987. The selection consisted of women with uncomplicated pregnancies. We studied serum concentration of 25(OH)D in 313 non-smoking and forty-six self-reported smoking pregnant women. Setting We hypothesize that pregnant smokers may have an increased risk of low 25(OH)D levels especially during winter months. Participants A control group from an unpublished pregnancy complication study consisting of 359 uncomplicated pregnancies. Individuals who reported that they do not smoke were considered 'non-smokers' (n 313) and those who reported continued smoking after the first trimester of pregnancy were considered 'smokers' (n 46). Results Smokers had significantly lower levels of 25(OH)D irrespective of sampling time (P
Subject: Pregnancy
Smoking
25-Hydroxyvitamin D
Vitamin D
SERUM 25-HYDROXYVITAMIN D
RISK
TIME
3142 Public health care science, environmental and occupational health
3143 Nutrition
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