Smoking during pregnancy reduces vitamin D levels in a Finnish birth register cohort

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dc.contributor University of Helsinki, Immunobiology Research Program en
dc.contributor University of Helsinki, Pregnancy and Genes en
dc.contributor University of Helsinki, HUS Gynecology and Obstetrics en
dc.contributor.author Lokki, A. Inkeri
dc.contributor.author Heikkinen-Eloranta, Jenni
dc.contributor.author Öhman, Hanna
dc.contributor.author Heinonen, Seppo
dc.contributor.author Surcel, Heljä-Marja
dc.contributor.author Nielsen, Henriette Svarre
dc.date.accessioned 2020-07-08T05:54:01Z
dc.date.available 2020-07-08T05:54:01Z
dc.date.issued 2020-05
dc.identifier.citation Lokki , A I , Heikkinen-Eloranta , J , Öhman , H , Heinonen , S , Surcel , H-M & Nielsen , H S 2020 , ' Smoking during pregnancy reduces vitamin D levels in a Finnish birth register cohort ' , Public Health Nutrition , vol. 23 , no. 7 , 1368980018003932 , pp. 1273-1277 . https://doi.org/10.1017/S1368980018003932 en
dc.identifier.issn 1368-9800
dc.identifier.other PURE: 137127059
dc.identifier.other PURE UUID: bdc84125-c3d7-4c31-ae87-db5dc3f05320
dc.identifier.other WOS: 000526368700016
dc.identifier.other ORCID: /0000-0003-4397-8415/work/74068495
dc.identifier.uri http://hdl.handle.net/10138/317499
dc.description.abstract Objective Maternal vitamin D level in pregnancy may have implications for both the mother and fetus. Deficiency of vitamin D has been linked to several pregnancy complications and fetal skeletal health. Smoking has been associated with reduced serum level of the vitamin D metabolite, 25-hydroxyvitamin D (25(OH)D). Design A nested case-control study within the Finnish Maternity Cohort, a population-based cohort which includes first-trimester sera from 98 % of pregnancies in Finland since 1987. The selection consisted of women with uncomplicated pregnancies. We studied serum concentration of 25(OH)D in 313 non-smoking and forty-six self-reported smoking pregnant women. Setting We hypothesize that pregnant smokers may have an increased risk of low 25(OH)D levels especially during winter months. Participants A control group from an unpublished pregnancy complication study consisting of 359 uncomplicated pregnancies. Individuals who reported that they do not smoke were considered 'non-smokers' (n 313) and those who reported continued smoking after the first trimester of pregnancy were considered 'smokers' (n 46). Results Smokers had significantly lower levels of 25(OH)D irrespective of sampling time (P en
dc.format.extent 5
dc.language.iso eng
dc.relation.ispartof Public Health Nutrition
dc.rights en
dc.subject Pregnancy en
dc.subject Smoking en
dc.subject 25-Hydroxyvitamin D en
dc.subject Vitamin D en
dc.subject SERUM 25-HYDROXYVITAMIN D en
dc.subject RISK en
dc.subject TIME en
dc.subject 3142 Public health care science, environmental and occupational health en
dc.subject 3143 Nutrition en
dc.title Smoking during pregnancy reduces vitamin D levels in a Finnish birth register cohort en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1017/S1368980018003932
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/acceptedVersion
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