Personal Autonomy as Quality of Life Predictor for Multiple Sclerosis Patients

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Padureanu , R , Albu , C V , Pirici , I , Mititelu , R R , Subtirelu , M S , Turcu-Stiolica , R A , Sintonen , H , Padureanu , V & Turcu-Stiolica , A 2020 , ' Personal Autonomy as Quality of Life Predictor for Multiple Sclerosis Patients ' , Journal of clinical medicine , vol. 9 , no. 5 , 1349 .

Title: Personal Autonomy as Quality of Life Predictor for Multiple Sclerosis Patients
Author: Padureanu, Rodica; Albu, Carmen Valeria; Pirici, Ionica; Mititelu, Radu Razvan; Subtirelu, Mihaela Simona; Turcu-Stiolica, Razvan Aurelian; Sintonen, Harri; Padureanu, Vlad; Turcu-Stiolica, Adina
Contributor organization: Clinicum
Harri Sintonen Research Group
Department of Public Health
University of Helsinki
HUS Helsinki and Uusimaa Hospital District
Date: 2020-05
Language: eng
Number of pages: 12
Belongs to series: Journal of clinical medicine
ISSN: 2077-0383
Abstract: Multiple sclerosis (MS) is a chronic, severe disease, characterized by a progressive alteration in neuronal transmission, which decreases personal independence and quality of life (QoL). This study aimed to investigate the relationship between QoL and personal autonomy in patients with MS, as well as its correlation with age, educational level, and diseases severity. Twenty-six MS patients were followed-up for six months. All patients completed the 15D questionnaire two times: at T0, when they started a new treatment, and at T1 after six months of treatment. At the end point, all patients completed the Personal Autonomy Questionnaire. The average patient age was 43 years (SD = 10), and 89% of them were female. The mean severity and duration of MS were 3.5 (SD = 1.75) and 9.5 (SD = 5.1), respectively. The average QoL of MS patients at T0 was 0.66 (SD = 0.18), and that at T1 was 0.71 (SD = 0.16). The scores of patients with different types of MS, i.e., relapsing-remitting MS (RRMS) or secondary progressive MS (SPMS), were compared. SPMS patients were older than RRMS patients (mean age 47.5 vs. 39.7 years; p = 0.032), and more RRMS patients were working (0.014). SPMS patients described the same QoL and personal autonomy as RRMS patients. Results from bivariate correlation analyses showed a significant relationship between QoL and age, education, and severity of MS. Also, the analysis showed no significant correlation between QoL and personal autonomy.
Subject: multiple sclerosis
quality of life
3121 General medicine, internal medicine and other clinical medicine
3112 Neurosciences
3124 Neurology and psychiatry
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion

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