Diagnosis of central disorders of hypersomnolence: A reappraisal by European experts

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http://hdl.handle.net/10138/318361

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Lammers , G J , Bassetti , C L A , Dolenc-Groselj , L , Jennum , P J , Kallweit , U , Khatami , R , Lecendreux , M , Manconi , M , Mayer , G , Partinen , M , Plazzi , G , Reading , P J , Santamaria , J , Sonka , K & Dauvilliers , Y 2020 , ' Diagnosis of central disorders of hypersomnolence: A reappraisal by European experts ' , Sleep Medicine Reviews , vol. 52 , 101306 . https://doi.org/10.1016/j.smrv.2020.101306

Title: Diagnosis of central disorders of hypersomnolence: A reappraisal by European experts
Author: Lammers, Gert Jan; Bassetti, Claudio L.A.; Dolenc-Groselj, Leja; Jennum, Poul J.; Kallweit, Ulf; Khatami, Ramin; Lecendreux, Michel; Manconi, Mauro; Mayer, Geert; Partinen, Markku; Plazzi, Giuseppe; Reading, Paul J.; Santamaria, Joan; Sonka, Karel; Dauvilliers, Yves
Contributor: University of Helsinki, Department of Neurosciences
Date: 2020-08
Language: eng
Number of pages: 11
Belongs to series: Sleep Medicine Reviews
ISSN: 1087-0792
URI: http://hdl.handle.net/10138/318361
Abstract: Summary The aim of this European initiative is to facilitate a structured discussion to improve the next edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter on central disorders of hypersomnolence. The ultimate goal for a sleep disorders classification is to be based on the underlying neurobiological causes of the disorders with clear implication for treatment or, ideally, prevention and or healing. The current ICSD classification, published in 2014, inevitably has important shortcomings, largely reflecting the lack of knowledge about the precise neurobiological mechanisms underlying the majority of sleep disorders we currently delineate. Despite a clear rationale for the present structure, there remain important limitations that make it difficult to apply in routine clinical practice. Moreover, there are indications that the current structure may even prevent us from gaining relevant new knowledge to better understand certain sleep disorders and their neurobiological causes. We suggest the creation of a new consistent, complaint driven, hierarchical classification for central disorders of hypersomnolence; containing levels of certainty, and giving diagnostic tests, particularly the MSLT, a weighting based on its specificity and sensitivity in the diagnostic context. We propose and define three diagnostic categories (with levels of certainty): 1/“Narcolepsy” 2/“Idiopathic hypersomnia”, 3/“Idiopathic excessive sleepiness” (with subtypes)
Subject: 3112 Neurosciences
Sleep
Classification
Diagnosis
Hypersomnolence
Hypersomnia
Excessive daytime sleepiness
Narcolepsy
Cataplexy
Fatigue
MSLT
Sleep inertia
3124 Neurology and psychiatry
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