Attention-Deficit/Hyperactivity Disorder Patients May Have Undiagnosed Narcolepsy

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http://hdl.handle.net/10138/318372

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Wilenius , L & Partinen , M 2020 , ' Attention-Deficit/Hyperactivity Disorder Patients May Have Undiagnosed Narcolepsy ' , Curēus , vol. 12 , no. 6 , 8436 . https://doi.org/10.7759/cureus.8436

Title: Attention-Deficit/Hyperactivity Disorder Patients May Have Undiagnosed Narcolepsy
Author: Wilenius, Lukas; Partinen, Markku
Contributor: University of Helsinki, Neurologian yksikkö
University of Helsinki, Department of Neurosciences
Date: 2020-06-04
Language: eng
Number of pages: 9
Belongs to series: Curēus
ISSN: 2168-8184
URI: http://hdl.handle.net/10138/318372
Abstract: Background Attention-deficit/hyperactivity disorder (ADHD) patients have many comorbidities. Narcoleptic patients have a big prevalence of ADHD (15%-30%). Both groups suffer from similar symptoms and benefit from the same class of medications. As such, narcolepsy could be masked in ADHD patients. Low serum ferritin has been found both in ADHD patients as well as in patients with narcolepsy. Materials & methods We enrolled 26 participants (14 ADHD patients and 12 controls). They answered several questionnaires, and blood samples were obtained from 20 participants. We had clear exclusion criteria. Results Using the Ullanlinna Narcolepsy Scale (UNS), we identified three possible narcolepsy patients within the ADHD group and no suspects in the control group. There was a statistically significant negative correlation between serum iron levels and ADHD symptom severity. No correlation was found measuring serum ferritin levels. Conclusions Narcolepsy may be more common within ADHD patients than in the general population. Some of these patients could benefit from a change in medication. Low serum iron and ferritin levels could he relevant in ADHD pathophysiology. This requires further exploratory research.
Subject: attention deficit hyperactivity disorder (adhd)
narcolcpsy
serum iron
scrum ferritin
adult adhd
excessive daytime sleepiness
cataplexy
DEFICIT HYPERACTIVITY DISORDER
IRON-DEFICIENCY
ATTENTION
CHILDREN
CATAPLEXY
SYMPTOMS
ADHD
3121 General medicine, internal medicine and other clinical medicine
3112 Neurosciences
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