Characteristics of Laryngeal Osteosarcoma : A Critical Review

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dc.contributor University of Helsinki, HUS Head and Neck Center en
dc.contributor University of Helsinki, HUS Head and Neck Center en
dc.contributor.author Mäkitie, Antti A.
dc.contributor.author Devaney, Kenneth O.
dc.contributor.author Baujat, Bertrand
dc.contributor.author Almangush, Alhadi
dc.contributor.author Ferlito, Alfio
dc.date.accessioned 2020-08-31T14:17:02Z
dc.date.available 2020-08-31T14:17:02Z
dc.date.issued 2020-06
dc.identifier.citation Mäkitie , A A , Devaney , K O , Baujat , B , Almangush , A & Ferlito , A 2020 , ' Characteristics of Laryngeal Osteosarcoma : A Critical Review ' , Oncology and therapy , vol. 8 , no. 1 , pp. 33-44 . https://doi.org/10.1007/s40487-020-00110-8 en
dc.identifier.issn 2366-1070
dc.identifier.other PURE: 134078261
dc.identifier.other PURE UUID: 32e7215d-ad81-4fc2-b5b7-5458366a86b4
dc.identifier.other WOS: 000518174300001
dc.identifier.uri http://hdl.handle.net/10138/318879
dc.description.abstract Laryngeal sarcomas constitute an extremely rare entity among head and neck malignancies. Furthermore, most of them are chondrosarcomas, and the osteogenic form remains a true rarity. In general, there is a lack of information on the characteristics of laryngeal osteosarcoma. Thus, we sought to critically review the existing world literature on laryngeal osteosarcoma in order to develop a more accurate clinicopathological profile of this malignancy. Laryngeal osteosarcoma has a predilection for elderly male patients, as 87% were male in the present series and the mean age was 62 years (range 32-80), and without a direct association with tobacco exposure. Osteosarcoma of the larynx is typically a highly malignant neoplasm that metastasizes early, has a propensity for hematogenous spread and also has a marked tendency to recur. Twelve (41%) out of the 29 cases in the present review with follow-up data had metastatic disease. The aspects that distinguish osteosarcoma from its differential diagnostic alternatives are discussed in this review. en
dc.format.extent 12
dc.language.iso eng
dc.relation.ispartof Oncology and therapy
dc.rights en
dc.subject Larynx en
dc.subject Osteosarcoma en
dc.subject Radiotherapy en
dc.subject Sarcoma en
dc.subject Surgery en
dc.subject OSTEO-SARCOMA en
dc.subject SOFT-TISSUE en
dc.subject 3122 Cancers en
dc.title Characteristics of Laryngeal Osteosarcoma : A Critical Review en
dc.type Review Article
dc.identifier.doi https://doi.org/10.1007/s40487-020-00110-8
dc.type.uri info:eu-repo/semantics/other
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