Narrowband ultraviolet B phototherapy improves quality of life of psoriasis and atopic dermatitis patients up to 3 months : Results from an observational multicenter study

Show full item record



Permalink

http://hdl.handle.net/10138/318906

Citation

Vakeva , L , Niemelä , S , Lauha , M , Pasternack , R , Hannuksela-Svahn , A , Hjerppe , A , Joensuu , A , Soronen , M , Ylianttila , L , Pastila , R , Kautiainen , H , Snellman , E , Grönroos , M & Karppinen , T 2019 , ' Narrowband ultraviolet B phototherapy improves quality of life of psoriasis and atopic dermatitis patients up to 3 months : Results from an observational multicenter study ' , Photodermatology, Photoimmunology & Photomedicine , vol. 35 , no. 5 , pp. 332-338 . https://doi.org/10.1111/phpp.12479

Title: Narrowband ultraviolet B phototherapy improves quality of life of psoriasis and atopic dermatitis patients up to 3 months : Results from an observational multicenter study
Author: Vakeva, Liisa; Niemelä, Sirkka; Lauha, Meri; Pasternack, Rafael; Hannuksela-Svahn, Anna; Hjerppe, Anna; Joensuu, Adrienn; Soronen, Minna; Ylianttila, Lasse; Pastila, Riikka; Kautiainen, Hannu; Snellman, Erna; Grönroos, Mari; Karppinen, Toni
Contributor organization: Staff Services
HUS Inflammation Center
Department of Dermatology, Allergology and Venereology
Clinicum
Department of General Practice and Primary Health Care
HUS Helsinki and Uusimaa Hospital District
HYKS erva
Päijät-Häme Welfare Consortium
Date: 2019-09
Language: eng
Number of pages: 7
Belongs to series: Photodermatology, Photoimmunology & Photomedicine
ISSN: 0905-4383
DOI: https://doi.org/10.1111/phpp.12479
URI: http://hdl.handle.net/10138/318906
Abstract: Background/Purpose Narrowband UVB phototherapy is a common treatment modality in psoriasis and atopic dermatitis, but evidence of its actual effect in clinical setting is sparse. Our aim was to assess the effectiveness and costs of narrowband UVB phototherapy in psoriasis and atopic dermatitis in clinical setting. Methods We observed 207 psoriasis patients and 144 atopic dermatitis patients in eight centers. SAPASI, PO-SCORAD, and VAS measures were used at baseline, at the end, and 3 months after the narrowband UVB phototherapy course. Quality of life was measured using Dermatology Life Quality Index (DLQI), and costs were assessed using a questionnaire. Results In both psoriasis and atopic dermatitis, the DLQI and Self-Administrated PASI (SAPASI)/Patient-Oriented SCORAD (PO-SCORAD) improved significantly and the results remained improved for at least 3 months in both groups. Alleviation of pruritus correlated with better quality of life in both patient groups. We reported slight redness and burning side effects which were due to lack of MED testing. Self-administered tools proved to be useful in evaluating pruritus and severity of the disease in psoriasis and atopic dermatitis. Mean patient costs were 310 euro and 21 hours of time, and mean costs for the healthcare provider were 810 euro. Conclusion In psoriasis, narrowband UVB is a very efficient treatment in clinical setting, whereas in atopic dermatitis, more studies are needed to determine the best dosage.
Subject: Dermatology Life Quality Index
Patient-Oriented SCORAD
Psoriasis Area and Severity Index
Scoring of Atopic Dermatitis
Self-Administrated PASI
UVB PHOTOTHERAPY
INDEX
HELIOTHERAPY
PHOTOCHEMOTHERAPY
S3-GUIDELINES
SEVERITY
EFFICACY
SCORAD
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: acceptedVersion


Files in this item

Total number of downloads: Loading...

Files Size Format View
V_kev_et_al_201 ... munology_Photomedicine.pdf 630.5Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record