Male Sexual Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood : A Multicenter Study

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Pysyväisosoite

http://hdl.handle.net/10138/319184

Lähdeviite

Haavisto , A , Mathiesen , S , Suominen , A , Lähteenmäki , P , Sorensen , K , Ifversen , M , Juul , A , Nielsen , M M , Müller , K & Jahnukainen , K 2020 , ' Male Sexual Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood : A Multicenter Study ' , Cancers , vol. 12 , no. 7 , 1786 . https://doi.org/10.3390/cancers12071786

Julkaisun nimi: Male Sexual Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood : A Multicenter Study
Tekijä: Haavisto, Anu; Mathiesen, Sidsel; Suominen, Anu; Lähteenmäki, Päivi; Sorensen, Kaspar; Ifversen, Marianne; Juul, Anders; Nielsen, Malene Mejdahl; Müller, Klaus; Jahnukainen, Kirsi
Tekijän organisaatio: Department of Psychology and Logopedics
University of Helsinki
Children's Hospital
HUS Children and Adolescents
Helsinki University Hospital Area
Clinicum
Päiväys: 2020-07
Kieli: eng
Sivumäärä: 12
Kuuluu julkaisusarjaan: Cancers
ISSN: 2072-6694
DOI-tunniste: https://doi.org/10.3390/cancers12071786
URI: http://hdl.handle.net/10138/319184
Tiivistelmä: There are many known endocrine complications after allogeneic hematopoietic stem cell transplantation (HSCT) in childhood including increased risk of biochemical hypogonadism. However, little is known about sexuality in adulthood following childhood HSCT. In this multicenter study, sexual functions and possible risk factors were assessed comprehensively in two national cohorts (Finland and Denmark) of male adult survivors of childhood HSCT. Compared to a healthy control group (n= 56), HSCT survivors (n= 97) reported less sexual fantasies, poorer orgasms, lower sexual activity with a partner and reduced satisfaction with their sex life, even in the presence of normal erectile functions and a similar frequency of autoerotic acts. Of the HSCT survivors, 35% were cohabitating/married and 66% were sexually active. Risk factors for poorer self-reported sexual functions were partner status (not cohabitating with a partner), depressive symptoms, CNS and testicular irradiation. Sexual dysfunction increased by age in the HSCT group with a pace comparable to that of the control group. However, because of the lower baseline level of sexual functions in the HSCT group, they will reach the level of clinically significant dysfunction at a younger age. Hence, male survivors of childhood HSCT should be interviewed in detail about their sexual health beyond erectile functions.
Avainsanat: HSCT
children
long-term survivors
pediatric cancer
sexual dysfunction
late effects
QUALITY-OF-LIFE
BONE-MARROW-TRANSPLANTATION
LONG-TERM SURVIVORS
CANCER SURVIVORS
ADULT SURVIVORS
OUTCOMES
DYSFUNCTION
DEPRESSION
MALIGNANCY
PROJECT
3123 Gynaecology and paediatrics
3122 Cancers
Vertaisarvioitu: Kyllä
Tekijänoikeustiedot: cc_by
Pääsyrajoitteet: openAccess
Rinnakkaistallennettu versio: publishedVersion


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