Male Sexual Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood : A Multicenter Study

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http://hdl.handle.net/10138/319184

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Haavisto , A , Mathiesen , S , Suominen , A , Lähteenmäki , P , Sorensen , K , Ifversen , M , Juul , A , Nielsen , M M , Müller , K & Jahnukainen , K 2020 , ' Male Sexual Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood : A Multicenter Study ' , Cancers , vol. 12 , no. 7 , 1786 . https://doi.org/10.3390/cancers12071786

Titel: Male Sexual Function after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood : A Multicenter Study
Författare: Haavisto, Anu; Mathiesen, Sidsel; Suominen, Anu; Lähteenmäki, Päivi; Sorensen, Kaspar; Ifversen, Marianne; Juul, Anders; Nielsen, Malene Mejdahl; Müller, Klaus; Jahnukainen, Kirsi
Upphovmannens organisation: Department of Psychology and Logopedics
University of Helsinki
Children's Hospital
HUS Children and Adolescents
Helsinki University Hospital Area
Clinicum
Datum: 2020-07
Språk: eng
Sidantal: 12
Tillhör serie: Cancers
ISSN: 2072-6694
DOI: https://doi.org/10.3390/cancers12071786
Permanenta länken (URI): http://hdl.handle.net/10138/319184
Abstrakt: There are many known endocrine complications after allogeneic hematopoietic stem cell transplantation (HSCT) in childhood including increased risk of biochemical hypogonadism. However, little is known about sexuality in adulthood following childhood HSCT. In this multicenter study, sexual functions and possible risk factors were assessed comprehensively in two national cohorts (Finland and Denmark) of male adult survivors of childhood HSCT. Compared to a healthy control group (n= 56), HSCT survivors (n= 97) reported less sexual fantasies, poorer orgasms, lower sexual activity with a partner and reduced satisfaction with their sex life, even in the presence of normal erectile functions and a similar frequency of autoerotic acts. Of the HSCT survivors, 35% were cohabitating/married and 66% were sexually active. Risk factors for poorer self-reported sexual functions were partner status (not cohabitating with a partner), depressive symptoms, CNS and testicular irradiation. Sexual dysfunction increased by age in the HSCT group with a pace comparable to that of the control group. However, because of the lower baseline level of sexual functions in the HSCT group, they will reach the level of clinically significant dysfunction at a younger age. Hence, male survivors of childhood HSCT should be interviewed in detail about their sexual health beyond erectile functions.
Subject: HSCT
children
long-term survivors
pediatric cancer
sexual dysfunction
late effects
QUALITY-OF-LIFE
BONE-MARROW-TRANSPLANTATION
LONG-TERM SURVIVORS
CANCER SURVIVORS
ADULT SURVIVORS
OUTCOMES
DYSFUNCTION
DEPRESSION
MALIGNANCY
PROJECT
3123 Gynaecology and paediatrics
3122 Cancers
Referentgranskad: Ja
Licens: cc_by
Användningsbegränsning: openAccess
Parallelpublicerad version: publishedVersion


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