Diffusion Tensor Imaging is associated with motor outcomes of very preterm born children at 11 years of age

Show full item record



Permalink

http://hdl.handle.net/10138/319230

Citation

the PIPARI Study Group , Lahti , K , Saunavaara , V , Munck , P , Uusitalo , K , Koivisto , M , Parkkola , R & Haataja , L 2020 , ' Diffusion Tensor Imaging is associated with motor outcomes of very preterm born children at 11 years of age ' , Acta Paediatrica , vol. 109 , no. 4 , pp. 738-745 . https://doi.org/10.1111/apa.15004

Title: Diffusion Tensor Imaging is associated with motor outcomes of very preterm born children at 11 years of age
Author: the PIPARI Study Group; Lahti, Katri; Saunavaara, Virva; Munck, Petriina; Uusitalo, Karoliina; Koivisto, Mari; Parkkola, Riitta; Haataja, Leena
Contributor: University of Helsinki, Department of Psychology and Logopedics
University of Helsinki, HUS Children and Adolescents
Date: 2020-04
Language: eng
Number of pages: 8
Belongs to series: Acta Paediatrica
ISSN: 0803-5253
URI: http://hdl.handle.net/10138/319230
Abstract: Abstract Aim Very preterm children born less than 32 weeks of gestation are at risk for motor difficulties such as cerebral palsy and developmental coordination disorder. This study explores the association between diffusion tensor imaging metrics at term and motor outcomes at 11 years of age. Methods A cohort of 37 very preterm infants (mean gestational age 29 4/7, SD 2 0/7) born in 2004-2006 in Turku University Hospital underwent diffusion tensor imaging at term. A region-of-interest analysis of fractional anisotropy and mean diffusivity was performed. Motor outcomes at 11 years of age were measured with the Movement Assessment Battery for Children ? Second Edition. Results The diffusion metrics of the corpus callosum (genu p=0.005, splenium p=0.049), the left corona radiata (p=0.035) and the right optic radiation (p=0.017) were related to later motor performance. Mean diffusivity decreased and fractional anisotropy increased in proportion to the improving performance. Conclusion The diffusion metrics of the genu and splenium of the corpus callosum, the left corona radiata and the right optic radiation at term were associated with motor skills at 11 years of age. Diffusion tensor imaging should be further studied as a potential tool in recognising children at risk for motor impairment.
Subject: Developmental coordination disorder
diffusion tensor imaging
motor development
Movement Assessment Battery for Children – Second Edition
very preterm infants
GAIT
LOW-BIRTH-WEIGHT
MRI
ABNORMALITIES
developmental coordination disorder
DEVELOPMENTAL COORDINATION DISORDER
WHITE-MATTER TRACTS
NEURODEVELOPMENT
TRACTOGRAPHY
INFANTS
Movement Assessment Battery for Children-Second Edition
CEREBRAL-PALSY
3123 Gynaecology and paediatrics
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
Lahti_et_al_2019_Acta_Paediatrica.pdf 914.7Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record