The Association between Race and Survival among Pediatric Patients with Neuroblastoma in the US between 1973 and 2015

Show full item record



Permalink

http://hdl.handle.net/10138/319318

Citation

Farouk , F S , Viqar , O A , Sheikh , Z , Castro , G & Barengo , N C 2020 , ' The Association between Race and Survival among Pediatric Patients with Neuroblastoma in the US between 1973 and 2015 ' , International Journal of Environmental Research and Public Health , vol. 17 , no. 14 , 5119 . https://doi.org/10.3390/ijerph17145119

Title: The Association between Race and Survival among Pediatric Patients with Neuroblastoma in the US between 1973 and 2015
Author: Farouk, Farouk S.; Viqar, Omar A.; Sheikh, Zaid; Castro, Grettel; Barengo, Noel C.
Contributor: University of Helsinki, Department of Public Health
Date: 2020-07
Language: eng
Number of pages: 9
Belongs to series: International Journal of Environmental Research and Public Health
ISSN: 1661-7827
URI: http://hdl.handle.net/10138/319318
Abstract: Background: Conclusive information regarding the influence of race on survival among neuroblastoma patients is limited. Our objective is to investigate the association between race and cause-specific survival in pediatric patients diagnosed with neuroblastoma in the US between 1973 and 2015.Methods: This was a retrospective cohort study using the Surveillance, Epidemiology, and End Result (SEER) database. Patients aged 17 and younger of black, white, or Asian Pacific Islander (API) race diagnosed with neuroblastoma from 1973-2015 were included (n = 2,119). The outcome variable was time from diagnosis to death. Covariates included age, gender, ethnicity, stage, tumor site, and year of diagnosis. Cox proportional hazard models were used to calculate hazard ratios and 95% confidence intervals.Results: There were no statistically significant differences in the hazard of survival for blacks (HR 0.93; 95% confidence interval (CI) 0.74-1.16) or API (HR 1.02; 95% CI 0.76-1.37) compared with whites. However, patients diagnosed between 2000-2004 (HR 0.46; 95% CI 0.36-0.59) and 2005-2015 (HR 0.33; 95% CI 0.26-0.41) had decreased hazards of death when compared to patients treated during 1973 to 1999.Conclusions: No association between race and survival time was found. However, survival improved among all patients treated during 2000-2004 and 2005-2015 compared with those treated before the year 2000, leading to a narrowing of the racial disparity based on survival.
Subject: neuroblastoma
neoplasms
child
ethnic groups
epidemiology
mortality
population cohort
TUMOR SITE
RISK GROUP
CHILDHOOD
CANCER
CHILDREN
AGE
3142 Public health care science, environmental and occupational health
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
ijerph_17_05119_v2.pdf 636.3Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record