Resection margins and local recurrences of impalpable breast cancer : Comparison between radioguided occult lesion localization (ROLL) and radioactive seed localization (RSL)

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dc.contributor University of Helsinki, HUS Comprehensive Cancer Center en
dc.contributor University of Helsinki, HUS Medical Imaging Center en
dc.contributor University of Helsinki, HUS Comprehensive Cancer Center en
dc.contributor University of Helsinki, HUS Comprehensive Cancer Center en
dc.contributor University of Helsinki, Department of Oncology en
dc.contributor University of Helsinki, HUSLAB en
dc.contributor University of Helsinki, HUS Comprehensive Cancer Center en
dc.contributor University of Helsinki, HUS Comprehensive Cancer Center en
dc.contributor.author Niinikoski, Laura
dc.contributor.author Hukkinen, Katja
dc.contributor.author Leidenius, Marjut H. K.
dc.contributor.author Vaara, Paivi
dc.contributor.author Voynov, Aleksandar
dc.contributor.author Heikkila, Paivi
dc.contributor.author Mattson, Johanna
dc.contributor.author Meretoja, Tuomo J.
dc.date.accessioned 2020-09-15T21:42:11Z
dc.date.available 2020-10-22T07:45:38Z
dc.date.issued 2019-10
dc.identifier.citation Niinikoski , L , Hukkinen , K , Leidenius , M H K , Vaara , P , Voynov , A , Heikkila , P , Mattson , J & Meretoja , T J 2019 , ' Resection margins and local recurrences of impalpable breast cancer : Comparison between radioguided occult lesion localization (ROLL) and radioactive seed localization (RSL) ' , Breast , vol. 47 , pp. 93-101 . https://doi.org/10.1016/j.breast.2019.07.004 en
dc.identifier.issn 0960-9776
dc.identifier.other PURE: 126793494
dc.identifier.other PURE UUID: 19cd0cfe-15ad-4862-8d9e-128f1b6aab6a
dc.identifier.other WOS: 000482211900012
dc.identifier.other ORCID: /0000-0002-2691-0710/work/61901062
dc.identifier.uri http://hdl.handle.net/10138/319380
dc.description.abstract Objectives: The aim of this retrospective study is to compare surgical margins, reoperation rates and local recurrences after breast conserving surgery (BCS) using radioguided occult lesion localization (ROLL) or radioactive seed localization (RSL). Materials and methods: We reviewed 744 consecutive patients with impalpable primary invasive breast cancer who underwent BCS at Helsinki University Hospital between 2010 and 2012. ROLL was used in our unit until October 31st, 2011; from November 1st we changed localization method to RSL. Results: 318 patients underwent ROLL and 426 RSL. Patients in the RSL group had more often multifocal (p = 0.013) tumours. No statistically significant differences were found regarding tumour size, specimen weight, histology or grade of tumours or lymph node status. 42 (5.6%) patients were reoperated because of insufficient margins, 13 (4.1%) in the ROLL group and 29 (6.8%) in the RSL group. The reoperation rate was not different between the groups either in the univariable analysis (p = 0.112) or in the multivariable binary logistic regression analysis (p = 0.204). Risk factors for reoperations were multifocality of the tumour (p Conclusion: Reoperation rates and LRFS were comparable for ROLL and RSL in patients with impalpable breast cancer treated with BCS. (C) 2019 Elsevier Ltd. All rights reserved. en
dc.format.extent 9
dc.language.iso eng
dc.relation.ispartof Breast
dc.rights en
dc.subject Breast cancer en
dc.subject Breast conserving surgery en
dc.subject Radioguided occult lesion localization en
dc.subject Radioactive seed localization en
dc.subject Surgical margins en
dc.subject Local recurrence en
dc.subject WIRE-GUIDED LOCALIZATION en
dc.subject CONSERVING SURGERY en
dc.subject NODES en
dc.subject 3122 Cancers en
dc.subject 3123 Gynaecology and paediatrics en
dc.title Resection margins and local recurrences of impalpable breast cancer : Comparison between radioguided occult lesion localization (ROLL) and radioactive seed localization (RSL) en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1016/j.breast.2019.07.004
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
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