Long-Term Outcomes of a Therapist-Supported, Smartphone-Based Intervention for Elevated Symptoms of Depression and Anxiety : Quasiexperimental, Pre-Postintervention Study

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dc.contributor University of Helsinki, Department of Public Health en
dc.contributor.author Economides, Marcos
dc.contributor.author Ranta, Kristian
dc.contributor.author Nazander, Albert
dc.contributor.author Hilgert, Outi
dc.contributor.author Goldin, Philippe R.
dc.contributor.author Raevuori, Anu
dc.contributor.author Forman-Hoffman, Valerie
dc.date.accessioned 2020-09-15T21:42:14Z
dc.date.available 2020-10-25T03:58:50Z
dc.date.issued 2019-08-26
dc.identifier.citation Economides , M , Ranta , K , Nazander , A , Hilgert , O , Goldin , P R , Raevuori , A & Forman-Hoffman , V 2019 , ' Long-Term Outcomes of a Therapist-Supported, Smartphone-Based Intervention for Elevated Symptoms of Depression and Anxiety : Quasiexperimental, Pre-Postintervention Study ' , JMIR mhealth and uhealth , vol. 7 , no. 8 , 14284 . https://doi.org/10.2196/14284 en
dc.identifier.issn 2291-5222
dc.identifier.other PURE: 126802054
dc.identifier.other PURE UUID: 17c6a86e-3d2a-429e-8b89-03883f1ee79e
dc.identifier.other WOS: 000482790700001
dc.identifier.other ORCID: /0000-0001-7704-9441/work/71511743
dc.identifier.uri http://hdl.handle.net/10138/319383
dc.description.abstract Background: Depression is one of the most common mental health disorders and severely impacts one's physical, psychological, and social functioning. To address access barriers to care, we developed Ascend-a smartphone-delivered, therapist-supported, 8-week intervention based on several evidence-based psychological treatments for depression and anxiety. A previous feasibility study with 102 adults with elevated depression reported that Ascend is associated with a postintervention reduction in depression symptoms. Objective: We aimed to examine whether Ascend is associated with a reduction in symptoms of anxiety, and importantly, whether reductions in symptoms of depression and anxiety are maintained up to 12-months postintervention. Methods: We assessed whether the previously reported, end-of-treatment improvements seen in the 102 adults with elevated symptoms of depression extended up to 12 months posttreatment for depression symptoms (measured by the Patient Health Questionnaire-9 [PHQ-9]) and up to 6 months posttreatment for anxiety symptoms (added to the intervention later and measured using the Generalized Anxiety Disorder-7 [GAD-7] scale). We used linear mixed effects models with Tukey contrasts to compare time points and reported intention-to-treat statistics with a sensitivity analysis. Results: The intervention was associated with reductions in symptoms of depression that were maintained 12 months after the program (6.67-point reduction in PHQ-9 score, 95% CI 5.59-7.75; P= 10) reported clinically significant improvement at the 12-month follow-up (at least 50% reduction in PHQ-9 score and postprogram score Conclusions: There is limited evidence on whether outcomes associated with smartphone-based interventions for common mental health problems are maintained posttreatment. Participants who enrolled in Ascend experienced clinically significant reductions in symptoms of depression and anxiety that were maintained for up to 1 year and 6 months after the intervention, respectively. Future randomized trials are warranted to test Ascend as a scalable solution to the treatment of depression and anxiety. en
dc.format.extent 13
dc.language.iso eng
dc.relation.ispartof JMIR mhealth and uhealth
dc.rights en
dc.subject digital health en
dc.subject depression en
dc.subject anxiety en
dc.subject mindfulness en
dc.subject CBT en
dc.subject online intervention en
dc.subject smartphone intervention en
dc.subject COGNITIVE-BEHAVIORAL THERAPY en
dc.subject MENTAL-HEALTH INTERVENTIONS en
dc.subject PSYCHOLOGICAL TREATMENTS en
dc.subject METAANALYSIS en
dc.subject DISORDER en
dc.subject VALIDATION en
dc.subject RELAPSE en
dc.subject PHQ-9 en
dc.subject PSYCHOTHERAPY en
dc.subject PREVENTION en
dc.subject 3142 Public health care science, environmental and occupational health en
dc.title Long-Term Outcomes of a Therapist-Supported, Smartphone-Based Intervention for Elevated Symptoms of Depression and Anxiety : Quasiexperimental, Pre-Postintervention Study en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.2196/14284
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
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